37. Cancer chemotherapy IV. (Hormonal agents)

Question 1

Which are the group of drugs that can help in cancer treatment?

Answer 1

• Glucocorticoids
• Gonadal hormone modulators
  
  • Progestins
  • Antiestrogens
    
    • SERM
    • Estrogen receptor antagonists
    • Aromatase inhibitors
      
      • Non-steroidal
      • Steroidal
  • Antiandrogens
• GnRH modulators
  
  • Analogues
  • Antagonists
• Other

Question 2

Which are the glucocorticoids?

Answer 2

• Prednisolone
• Methylprednisolone
• Dexamethasone

Question 3

Which are the progestins?

Answer 3

• Medroxyprogesterone
• Megestrol

Question 4

Which are the SERM antiestrogens?

Answer 4

• Tamoxifen
• Toremifene

Question 5

Which are the estrogen receptor antagonist antiestrogen?

Answer 5

Fulvestrant

Question 6

Which are the steroidal aromatase inhibitors antiestrogens?

Answer 6

• Exemestane
• Formestane

Question 7

Which are the non-steroidal aromatase inhibitors antiestrogens?

Answer 7

• Anastrazole
• Letrozole

Question 8

Which are the antiandrogens?

Answer 8

• Steroid synthesis inhibitor:
  
  • Abirateron
• Androgen receptor blockers
  
  • Flutamide, bicalutamide*, *nilutamide
  • Cyproterone acetate

Question 9

Which are the GnRH analogues?

Answer 9

• Leuprolide
• Goserelin
• Triptorelin
• Buserelin

Question 10

Which are the GnRH antagonists?

Answer 10

• Ganirelix
• Abarelix
• Degarelix

Question 11

Which other hormonal drugs can help in the treatment of cancer?

Answer 11

Octreotide