26. Thyroid and antithyroid drugs. Hypothalamic and pituitary hormones

Question 1

Which are the thyroid hormones?

Answer 1

• Thyroxine (T₄)
• Triiodothyronine (T₃)

Question 2

What is the TRH analogue?

Answer 2

Protirelin

Question 3

What is the TSH analogue?

Answer 3

Thyrotropin alpha

Question 4

What is the replacement therapy of hypothyroidism?

Answer 4

• Levothyroxine (T₄)
• Liothyronine (T₃)

Question 5

Which are the drugs inhibiting thyroid hormone synthesis?

Answer 5

• Thioamides:
  
  • Propylthiouracil (PTU)
  • Methimazole

Question 6

Which are the hypothalamic hormone analogues?

Answer 6

• GHRH:
  
  • GHRH₄₀ and GHRH₄₄
  • Sermorelin (GHRH_1-29 acetate)
  • Tesamorelin
• GnRH:
  
  • ​Analogues
    
    • Leuprolide
    • Buserelin
    • Goserelin
    • Triptorelin
    • Nafarelin
  • Antagonists
    
    • Ganirelix
    • Abarelix
    • Degarelix
    • Cetrorelix

Question 7

Which are the GH analogues?

Answer 7

• ​Somatotropin
• Somatrem

Question 8

Which are the somatotropin (GH) receptor antagonists?

Answer 8

Pegvisomant

Question 9

Which are the somatostatin analogues?

Answer 9

• Octreotide, Lanreotide
• Pasireotide
• Telotristat
• Somatostatin-eumedica

Question 10

Which are the dopamin agonists for hyperprolactinemia?

Answer 10

• Bromocriptine
• Cabergoline
• Pergolide
• Quinagolide

Question 11

Which are the ACTH analogues?

Answer 11

Cosyntropin

Question 12

Which are the gonadotropin (FSH, LH) analogues?

Answer 12

• FSH:
  
  • ​​Follitropin alpha and beta
  • Urofollitropin
• LH:
  
  • ​Alpha-lutropin
  • hCG
  • rhCG
• Menotropins:
  
  • ​hMG

Question 13

Which are the neurohypophysis hormone analogues?

Answer 13

• Oxytocin
• Vasopressin
  
  • Desmopressin
  • Terlipressin