30. Agents used in anemias

Question 1

Which are the groups of agents used in anemia?

Answer 1

• Iron
  
  • Oral preparations
  • Parenteral preparations
• Vitamin B12 (cyanocobalamine, hydroxocobalamine)
• Vitamin B9 (folic acid)
• Erythropoietin, darbepoietin
• Myeloid groth factors
• Megakaryocyte growth factors

Question 2

Which are the oral preparations of iron?

Answer 2

• Containing ionic iron:
  
  • Ferrous-sulfate
  • Ferrous-fumarate
  • Ferrous-gluconate
• Complex iron preparations:
  
  • Fe(III)-hydroxide-polymaltose

Question 3

Which are the parenteral preparations of iron?

Answer 3

• Iron dextran
• Sodium ferric gluconate complex
• Iron-sucrose complex

Question 4

Which is the active form of vitamin B12?

Answer 4

Cyanocobalamine, hydroxocobalamine:

• Methylcobalamine

Question 5

Which are the drugs forms of EPO?

Answer 5

• Erythropoietin (epoetin alpha)
• Darbepoetin
• Beta epoetin methoxy-polyethylene-glycol

Question 6

Which are the myeloid growth factors?

Answer 6

• G-CSF
• GM-CSF
• Recombinant human G-CSF (filgrastim)
• Recombinant human GM-CSF (sargramostim)
• Pegfilgrastim

Question 7

Which are the megakarycyte growth factors?

Answer 7

• Oprelvekin (IL-11)
• TPO
  
  • Romiplostin
  • Eltrombopag