3.6 Staging of cancer Flashcards
Why do we stage cancer?
Planning treatment
Accurate communication between physicians
Assessment of treatment
Create a flowchart of management and treatment
When should staging be applied?
At the time of diagnosis
What is not part of staging?
Tumour grade
Histological subtype
Microscopic features
Patient symptoms
What is the T stage
Tumour Tx = not accessible T0 = no evidence of primary Tis = Carcinoma in situ (no invasion and not malignan) T1-4 = increasing size or local extent
What is teh N stage?
Node
Nx = not accessible
N0 = no regional lymph node mets
N1-3 = increasing involvement
What is the M stage
Metastases
M0 = no mets
M1 = mets
What is pT?
Pathologic tumour (stage has been determined after resection)
What is ypN
Pathologic stage of nodes post chemotherapy
What is R staging?
Residual tumour post resection
R0 = no residual tumour
R1 = microscopic residual tumour
R2 = macroscopic
What is sn staging?
Sentinel node involvement
What does ypN1(sn) mean?
after chemotherapy a sentinel node was positive
What is the T stage in breast cancer?
Tx = Primary cannot be assessed Tis = in situ disease only T0 = no primary T1 = 2 5cm T4 = tumour involving chest wall or skin
What is the N stage in breast cancer?
N0 = none N1 = 1-3 axillary nodes N2 = >3 axillary or apparent internal mammary N3= > = 10
What TNM is stage 1 breast cancer?
T1, N0, M0
What TNM is stage 2 breast ?
as soon as there is nodal involvement (only up to N1)
T0, T1 and T2 with N1 M0
OR
T3 N0 M0