3.3 Chemical Examination of Urine (Protein)

Question 1

Normal Values for protein?

Answer 1

<30mg/dl or <150 mg/day

Question 2

The glomerular filtration barrier is impermeable to proteins in general.

T or F

Answer 2

T

Question 3

Overflow proteinuria

a. Pre-renal
b. Renal (Glomerular)
c. Renal (Tubular)
d. Post renal

Answer 3

a

Question 4

Low molecular weight protein in the blood that overflows in the urine which is excreted readily

a. Pre-renal
b. Renal (Glomerular)
c. Renal (Tubular)
d. Post renal

Answer 4

a

Question 5

May relate to Fanconi Syndorme (Failure of PCT reabsorption)

a. Pre-renal
b. Renal (Glomerular)
c. Renal (Tubular)
d. Post renal

Answer 5

c

Question 6

Diabetic nephropathy

a. Pre-renal
b. Renal (Glomerular)
c. Renal (Tubular)
d. Post renal

Answer 6

b

Question 7

What is the earliest indicator for Diabetic Nephropathy?

Answer 7

Microalbuminuria

Question 8

Intravascular Hemolysis / Hemolytic disorder

a. Pre-renal
b. Renal (Glomerular)
c. Renal (Tubular)
d. Post renal

Answer 8

a

Question 9

Hemoglobin is the protein of interest

a. Pre-renal
b. Renal (Glomerular)
c. Renal (Tubular)
d. Post renal

Answer 9

a

Question 10

Muscle injury (Myoglobin)

a. Pre-renal
b. Renal (Glomerular)
c. Renal (Tubular)
d. Post renal

Answer 10

a

Question 11

Inflammation (APR)

a. Pre-renal
b. Renal (Glomerular)
c. Renal (Tubular)
d. Post renal

Answer 11

a

Question 12

Multiple myeloma (Light chain of IgG)

a. Pre-renal
b. Renal (Glomerular)
c. Renal (Tubular)
d. Post renal

Answer 12

a

Question 13

Bence Jones Protein from Multiple myeloma

a. Pre-renal
b. Renal (Glomerular)
c. Renal (Tubular)
d. Post renal

Answer 13

a

Question 14

Bence Jones is characterized with unique thermal sensitivity which has a ______ C and disappears at _____ C

Answer 14

40-60

100

Question 15

Lower UTI

a. Pre-renal
b. Renal (Glomerular)
c. Renal (Tubular)
d. Post renal

Answer 15

d

Question 16

In SSA TEST / Cold protein precipitation, it is a traditional test for Protein detrmination which differs from protein reagent strip test in that it detects BOTH ________ and _______

Answer 16

Albumins and globulins

Question 17

SSA test does not require heating

T or F

Answer 17

T

Question 18

Procedure for SSA test:

__mL of __% SS is added to __ mL of ____________ urine

Answer 18

3
3
3
Centrifuge

Question 19

One of the important observation after adding SSA is turbidity.’

T or F

Answer 19

T

Question 20

Degree of turbidity:

Noticeable tubidity (6-30)

a. Neg
b. Trace
c. 1+
d. 2+
e. 3+
f. 4+

Answer 20

b

Question 21

Degree of turbidity:

Turbidity w/ Granulation (100-200)

a. Neg
b. Trace
c. 1+
d. 2+
e. 3+
f. 4+

Answer 21

d

Question 22

Degree of turbidity:

Turbidity with granulation and flocculation (200-400)

a. Neg
b. Trace
c. 1+
d. 2+
e. 3+
f. 4+

Answer 22

e

Question 23

Degree of turbidity:

Distinct Turbidity with no granulation (30-100)

a. Neg
b. Trace
c. 1+
d. 2+
e. 3+
f. 4+

Answer 23

c

Question 24

Degree of turbidity:

Clumps of protein(>400)

a. Neg
b. Trace
c. 1+
d. 2+
e. 3+
f. 4+

Answer 24

f

Question 25

Degree of turbidity:

<6mg/dL

a. Neg
b. Trace
c. 1+
d. 2+
e. 3+
f. 4+

Answer 25

a

Question 26

Normal value of protein is from Neg only

T or F

Answer 26

F

Neg to trace

Question 27

Micral test is based on Enzyme immunoassay

Immunodip is based on immunochromatographic technique

T or F

Answer 27

T

Question 28

Test for microalbuminuria includes:

Micral test
Immunodiip
Albumin/Creatinine Ratio
Albumin Excretion Rate

T or F

Answer 28

T

Question 29

Significant result:

ACR: 30-300 mg
AER: 20-200 / mins or 30-300mg/24 hrs

T or F

Answer 29

T