3: S/S of Gynecologic Cancers

Question 1

Often asymptomatic. If signs and symptoms do become apparent, however, the most common presentation is a woman’s report of a vulvar lump or mass that may or may not be painful. There is often a prolonged history of vulvar pruritus, and vulvar bleeding, discharge, and dysuria may be present.

Answer 1

Vulvar cancer

Question 2

Ascites is common because of increased inflammation in response to metastatic cancer deposits on the peritoneum.

Answer 2

Ovarian cancer (Type 2 epithelial specifically)

Question 3

Adenocarcinoma of the vulva characterized by asymmetrical white and red scaly plaques on the vulva.

Answer 3

Extra-mammary Paget’s disease (Vulvar cancer)

Question 4

Appears as unusual macules or papules on the labia majora, and less commonly on the labia minora or clitoris.

Answer 4

Malignant melanoma (Vulvar cancer)

Question 5

Early stage is usually asymptomatic. If symptoms do occur, the most commonly noted are abnormal vaginal bleeding, such as postmenopausal bleeding, irregular menses, heavy menstrual flow, painless heavy menstrual bleeding, or postcoital bleeding. An abnormal vaginal discharge that is odiferous, watery, purulent, or mucoid may also be present. Late symptoms that suggest metastatic spread include bladder outlet obstruction, constipation, back pain, pelvic pain, pain during intercourse, and leg swelling

Answer 5

Cervical cancer

Question 6

Most common symptoms is abnormal uterine bleeding.
Advanced symptoms include pelvic pain, abdominal distention with or without pain, bloating, change in bowel or bladder pattern, and change in appetite.

Answer 6

Endometrial cancer

Question 7

In late stages, there may be a cauliflower-like growth.

Answer 7

Cervical cancer

Question 8

Silent disease
Vague symptoms:
Abdominal bloating and discomfort
Difficulty eating
Early satiety
Back pain
Changes in bowel patterns
Advanced disease:
Pelvic pressure
Anorexia
N/V
Ascites
Vaginal bleeding
Painful intercourse
Abdominal mass
Unexplained weight loss

Answer 8

Ovarian cancer

Question 9

The lesion is usually raised, and may be ulcerated, warty, or fleshy in appearance; alternatively, it may appear to be an area of squamous cell hyperplasia. Lesions may be single or multiple in number, and color can vary from white to gray, red to brown, or black. Most occur on the labia majora, although the labia minora, clitoris, and perineum are other possible primary sites. Women with advanced disease may present with a lump in the groin related to lymph node metastasis

Answer 9

Squamous cell vulvar cancer