3/16/17 #1 Flashcards

1
Q

Phosphatidylinositol 2nd Messenger System

A

GCPR > Phosopholipase C > IP3 > release of Ca > Protein Kinase C

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2
Q

Hernial Incarceration

A

Causes bowel obstruction (nausea, vomiting, abdominal pain/distention)

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3
Q

Methotrexate: MoA

A

Folic Acid metabolism inhibitor

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4
Q

PT vs PTT

A

PT: Extrinsic (VII)
PTT: Intrinsic (VIII, IX)

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5
Q

Celiac’s: Histo

A

Villous blunting/atrophy, crypt hyperplasia, Inflammation

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6
Q

Acute Contact Dermatitis: Hypersenstivity

A

Type IV, leading to edema and spongy epidermis (chronic becomes less edematous and more scaly)

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7
Q

B-blocker: thyroid storm MoA

A

Blocks T4 . T3 conversion, Blocks sypathetic action on target organs

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8
Q

Obturator nerve: motor action

A

Adduction of thigh

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9
Q

Clozapine: Indications

A

Treatment resistant Schizo, Schizo with suicidality

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10
Q

Cardiac Pacemaker Cells: Ion roles

A

Na: Slow depole
Ca: Rapid depole
K: Repole

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11
Q

Bipolar vs Major Depression: Diagonistc

A

Bipolar may be misdiagnoses as Major depression. Monotherapy may induce mania. Redflag: Rapid response to SSRIs (normally 2wks)

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12
Q

Axilary: Motor Innervations

A

Teres minor, deltoid

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13
Q

Mesothelioma: radiographic

A

Pleural thickening (smooth or nodular)

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14
Q

Pheochromocytoma: Signs and Symps

A

Headache, Sweating, HTN, tachycardia

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15
Q

Amniotic fluid embolism: Signs and Symps

A

DIC, cardiogenic shock, hypoxemic respiratory failure, seizure/coma

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16
Q

Scurvy: Signs and Symps

A

Gingival Bleeding, corkscrew hairs, malaise, lethargy, poor wound healing

17
Q

Enteric Bacteria: Vit Production

A

K and Folate

18
Q

renal angiomyolipoma: association

A

Tuberous Sclerosis (brain hartomas and ash-leaf skin lesions)

19
Q

IL-4: role

A

IgE Class switching

20
Q

Atrial naturetic peptide

A

vasolilator that leads to nateuresis and dieresis