2/26/17 Flashcards

1
Q

Buprenorphine - MoA

A

Partial Mu-opioid agonist with strong binding

Can precipitate withdrawals

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2
Q

Elastase Location

A

Neutrophils and Macrophages

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3
Q

Benzo DDIs

A

Alcohol, Barbs, Neuroleptics, 1st Gen antihistamines

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4
Q

Stage where Oocyte is resting prior to fertilization

A

Metaphase II

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5
Q

S. Pnemo: primary virulence factor

A

Polysaccaride capsule

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6
Q

Lymph Node Cell Distribution

A

B cells: germinal centers and primary follicles
B + T: outer cortex
T+ Dendrites: Parafollicular

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7
Q

Rough ER vs Smooth ER: production

A

Rough: Proteins
Smooth: steroids, phospholipids

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8
Q

Lamatrogine: Side Effects

A

Stevens Johnson Syndrome/ Toxic Epidermal Necrosis

Therefore: always watch for a rash

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9
Q

Benzos: Length of Action

A

Short: Triazolam, oxazepam, Midazolam
Medium: Alprazolam, Lorazepam, temzepam
Long: Diazepam, chlordiazepam, flurazepam

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10
Q

Testicular Lymph Drainage

A

Para-aortic

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11
Q

Median Nerve Passage: forearm

A

Between flexor digitorum profundus and flexor digitorum superficialais

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12
Q

CD21: Viral association

A

EBV

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13
Q

Post Pirandial insulin: type

A

Regular: best for IV

Lispro, Aspart, glulisine: best for post meal hyperglycemia

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14
Q

GnRH-Prolactin Feedback

A

Increases in Prolactin lead to decreases in GnRH

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15
Q

Raphe Nuclei: Neurotransmitter

A

Primarily serotonin

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16
Q

Sickle Cell: Viral infection + sequale

A

Parvo B19 > Aplastic Crisis

17
Q

Renal Infact: Signs

A

LDH Up, flank pain, hematuria, wedge lesion on CT

18
Q

Spleen: embryonic origins

A

Mesoderm

19
Q

Exercise and DM: risk

A

Hypoglycemia

20
Q

MS: Bladder Issues

A

Spastic bladder due to loss of distensibility

Leads to Residual volume

21
Q

Liver Cirrhosis: Signs

A

Jaundice, portal HTN, Hyperestrinism ( Spider angiomas + gynecomastia), hepatic disfunction

22
Q

MS: Conduction effect

A

Decrease of saltatory conduction due to demylenation

23
Q

NorEpi: MoA

A

Alpha 1: increases IP3
Alpha 2: decease in cAMP
Beta 1: increase in cAMP

NO Beta 2