2/12/17 Flashcards
Umbilical veins feeds into
IVC
Crigler Najjar Syndrome
Loss of UGT enzyme for conjugation
Common cause for neonatal jaudince
Hep B: Genetics
Circular, partial dsDNA
Phosphoribosyl Pryrophosphate (PRPP) Synthase function
Purine Synthesis
Part of Gout pathophys
Inflammatory cells responsible for Gout
Neutrophils
Antiphospholipid Syndrome: Definition
Venous/Arterial Thrombosis or recurrent miscarriages due to Antiphos Abs
OCD Treatment
SSRIs
Toxic Megacolon: Association and Diagnosis
Association: Ulcerative Colitis
Diagnosis: Plain Film Abdominal X-ray
Radial Nerve Injury
Weakness: Forearm, hand, Finger extensors
Sensory Loss: Posterior arm/forearm, dorsalateral hand, dorsal thumb
Anxiety Treatments
SSRI or SNRI
Pseudomonas Aeruginosa: Microbio
Motile aerobic GNR, Ox positive
DIC Labs
Plasma fibrinogin -Down
PTT - Up
Renal effects of hemolysis
Hemosiderosis
Primary biliary cirrhosis: Pathophys and Diagnosis
Pathophys: Autoimmune intra-hepatic bile duct destruction and cholestasis
Diag: Alk Phos - Up
Sever Night Itching
C-section: Risks with horizontal transaction of recus abdominus
Presence of Inf. Epigastric Arteries
Thiamine Deficiency: Diagnostic Labs
Increased Erythrocyte transketolase activity signify a deficiency of thiamine
Cortisol Effects: Immune and Neuro
Immune: suppression, neutrophilia, Increased infections
Neuro: psychosis, hypomania, sleep disturbances
Congenital Rubella: signs and prevention
Signs: Head/eye, ears, heart defects
Prevention: Preconceptive Live attenuated vaccination
Sphereocyte Labs
Smear: RBCs w/o Central Pallor
MCHC - Up
Nitroprusside Toxicity: Pathophys and Treatment
Pathophys: Breaks down into cyanide, leading to inhibition of mitochondrial ETC
Treatment: Sulfur Donors - Enhance Detox
Sodium Nitrate - promote Methemeoglobin (increased CN binding)
Hydroxycobalamine - Direct CN binding
Thoracocentesis: Insertion Points
Midclavicular: 6-8th Rib
Midaxillary: 8-10th
Paraverterbral: 10-12th
Reduces risk of lung injury, but penetration injury into abdomen still possible (Liver, spleen, etc)
Eukaryotic Translation Initiation Sequence
Kozak Sequence
Analog to Shine-Delgarno
Infant Vitamin Supplements
K and D
Paget’s Disease: Pathophys
Increased osteoclast/blast activity through mediation of M-CSF (macrophage colony-stimulating factor) and RANK-L (Receptor-Activated Nuclear Factor Kappa-B Ligand)
