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Question 1

Umbilical veins feeds into

Answer 1

IVC

Question 2

Crigler Najjar Syndrome

Answer 2

Loss of UGT enzyme for conjugation

Common cause for neonatal jaudince

Question 3

Hep B: Genetics

Answer 3

Circular, partial dsDNA

Question 4

Phosphoribosyl Pryrophosphate (PRPP) Synthase function

Answer 4

Purine Synthesis

Part of Gout pathophys

Question 5

Inflammatory cells responsible for Gout

Answer 5

Neutrophils

Question 6

Antiphospholipid Syndrome: Definition

Answer 6

Venous/Arterial Thrombosis or recurrent miscarriages due to Antiphos Abs

Question 7

OCD Treatment

Answer 7

SSRIs

Question 8

Toxic Megacolon: Association and Diagnosis

Answer 8

Association: Ulcerative Colitis

Diagnosis: Plain Film Abdominal X-ray

Question 9

Radial Nerve Injury

Answer 9

Weakness: Forearm, hand, Finger extensors

Sensory Loss: Posterior arm/forearm, dorsalateral hand, dorsal thumb

Question 10

Anxiety Treatments

Answer 10

SSRI or SNRI

Question 11

Pseudomonas Aeruginosa: Microbio

Answer 11

Motile aerobic GNR, Ox positive

Question 12

DIC Labs

Answer 12

Plasma fibrinogin -Down

PTT - Up

Question 13

Renal effects of hemolysis

Answer 13

Hemosiderosis

Question 14

Primary biliary cirrhosis: Pathophys and Diagnosis

Answer 14

Pathophys: Autoimmune intra-hepatic bile duct destruction and cholestasis

Diag: Alk Phos - Up
Sever Night Itching

Question 15

C-section: Risks with horizontal transaction of recus abdominus

Answer 15

Presence of Inf. Epigastric Arteries

Question 16

Thiamine Deficiency: Diagnostic Labs

Answer 16

Increased Erythrocyte transketolase activity signify a deficiency of thiamine

Question 17

Cortisol Effects: Immune and Neuro

Answer 17

Immune: suppression, neutrophilia, Increased infections

Neuro: psychosis, hypomania, sleep disturbances

Question 18

Congenital Rubella: signs and prevention

Answer 18

Signs: Head/eye, ears, heart defects

Prevention: Preconceptive Live attenuated vaccination

Question 19

Sphereocyte Labs

Answer 19

Smear: RBCs w/o Central Pallor

MCHC - Up

Question 20

Nitroprusside Toxicity: Pathophys and Treatment

Answer 20

Pathophys: Breaks down into cyanide, leading to inhibition of mitochondrial ETC

Treatment: Sulfur Donors - Enhance Detox
Sodium Nitrate - promote Methemeoglobin (increased CN binding)
Hydroxycobalamine - Direct CN binding

Question 21

Thoracocentesis: Insertion Points

Answer 21

Midclavicular: 6-8th Rib
Midaxillary: 8-10th
Paraverterbral: 10-12th

Reduces risk of lung injury, but penetration injury into abdomen still possible (Liver, spleen, etc)

Question 22

Eukaryotic Translation Initiation Sequence

Answer 22

Kozak Sequence

Analog to Shine-Delgarno

Question 23

Infant Vitamin Supplements

Answer 23

K and D

Question 24

Paget’s Disease: Pathophys

Answer 24

Increased osteoclast/blast activity through mediation of M-CSF (macrophage colony-stimulating factor) and RANK-L (Receptor-Activated Nuclear Factor Kappa-B Ligand)

Question 25

Site of Angiotensis I to II conversion

Answer 25

Small pulmonary vessels

Question 26

Collagen Types and Locations

Answer 26

I: Dermis, bone, tendon, ligaments, dentin, cornea, blood vessels, mature scars

II: Cartilage, Vitreous humor

III: Skin, lungs, intestine, blood vessels, bone marrow, lymph nodes, granulation tissue

IV: basement membrane