2/21/17

Question 1

Intraductal Papilloma: Signs and Histo

Answer 1

Bloody Nipple Discharge

Papillary Proliferation with fibrovascular cores

Question 2

Acute Intermittent Porphria: Pathophys and Signs/Symps

Answer 2

Auto Dom deficiency of Porphobiliogen Deaminase

Acute Abdominal Pain + Neuro Signs

Question 3

Lead Poisoning: Labs and Signs/Symps

Answer 3

ALA dehydratase: Down
Ferrochelatase: Down
Basophilic stippling

Microcytic anemia, constipation, metal status change

Question 4

Erythema Multiform VS Disseminated Herpes

Answer 4

Erythema Multiform: Target lesions on skin of extremities, face, trunk, neck (severe cases) oral mucosa

Diseminated Herpes: Predominately in ImmunoCompromised, diffuse vesicles with erythematous base

Question 5

Ischemia: Pathophys/Labs

Answer 5

Loss of ATP > Increase NADH > Inhibition of Pyruvate dehydrogenase > increase in Lactate > increase in Lactate Dehydrogenase

Question 6

Cystic Fibrosis: Pathphys

Answer 6

Mutation in Cl secretion leads to increased Na retention and thus water retention > thickened mucus

Question 7

Mycardial O2 use (compared to normal)

Answer 7

Increased

Question 8

Sign language: Writing or Interpreter

Answer 8

Interpreter

Question 9

Acute Pancreatitis due to Alcoholism: Labs

Answer 9

Increased Lipase, 2:1 AST/ALT/ marked elevation (liver damage), NO Gallstones, macrocytosis (due to malnutrition)

Question 10

Digoxin MoA/Cardiac Phys

Answer 10

Na/K ATPase inhibitor

Loss of Na Efflux leads to loss of Ca efflux due to Ca/NA pump

Question 11

Trapezius Weakness: Signs

Answer 11

Dropping Shoulder, impared abduction above horizontal, scapular winging

Question 12

Duodenum: 3rd Portion Overlays

Answer 12

L3, Abdominal Aorta, IVC, close to the SMA

Question 13

Infarct of Anterior Pons: Signs

Answer 13

Dysarthria, contralateral face palsy (corticobulbar tract)

Contralateral hemeparesis, babinski sign (Corticospinal tract)

Question 14

Candida Colonization Sites

Answer 14

GI tract including oral cavity

Question 15

HSV1: Microbio

Answer 15

Enveloped DsDNA

Question 16

Proteasome inhibition leads to

Answer 16

Apotosis

Question 17

Crohn’s and Gallstones: pathophys

Answer 17

Terminal ileal scaring > decreased bile acid re- absorption > cholesterol stone formation

Question 18

Tetrology of Fallot

Answer 18

VSD, Coarcation, Right sided Hypertrophy due to right sided outflow obstruction.

Question 19

Eosinophil Antiparasitic action

Answer 19

Antibody dependent cell mediated cytotoxicity

Question 20

Junctional vs Compound nevus

Answer 20

Junctional: Epidermal junction only

Compoound: epidermal + dermal expansion

Question 21

Rheumatoid arthritis: Sites

Answer 21

Small joints and cervical spine

Question 22

Fragile X: Signs

Answer 22

Neurobehavioral, pronounced forehead, large ears, long narrow face, prominent chin, macroorchidism

Question 23

Acute Panic Attack: Emergency relief

Answer 23

Benzodiazapines

Question 24

Epi: Sites of Action

Answer 24

Sympathetic Action on target organs Except Adrenal medulla and Sweat glands

Question 25

Preganglionic Symp receptor

Answer 25

Ach

Question 26

Hyperaldosteronism: Signs and Symps

Answer 26

HTN, HypoK, Alkalosis leading to weakness/parasthesia

Question 27

Histone Locations

Answer 27

H2A, H2B, H3, H4: inside histone core

H1: outside core, part of linear segments

Question 28

Teratoma: Path

Answer 28

Differentiated tissues