2/22/17 Flashcards
Pancreatic Divisium: signs and pathophys
Signs: recurrent pancreatitis
Pathophys: failure of ventral and dorsal bud fusion, leading to twin ducts: Ventral and Dorsal(dominant) duct
Pancreatic differentiation
Ventral: uncinate process, inferior/posterior head, major pancreatic duct
Dorsal: everything else
Fidoxomicin: Use and MoA
Use: C. Diff infection
RNA Pol Inhibitor
B-Blocker: MoA for HTN treatment
Block of Renin secretion leading to decrease in RAAS pathway
Locations: Broca and Wernicke
Broca: Inferior Frontal Gyrus
Wernicke: caudal superior temporal gyrus
Thiazide side effects
Hyper Ca, Hypo Na, HypoK, Metabolic Acidosis
DM: Overflow incontience mechanism
Loss of detrusor contractibility due to neuropathy, leading to increased post void residual volume
TTP and HUS: Common Symptoms
Platelet Activation, diffuse microvascular thrombosis, microangiopathic hemolytic anemia (with schistocytes) thrombocytopenia
TTP-HUS: Classic Pentad
fever, neurosymptoms, renal failure, anemia, thrombocytopenia, in setting of GI illness
Listeria: Growth Conditions
Can grow at refrigeration temperatures due to being an intracellular pathogen
Clozapine: Side Effects
Aganulocytosis, seizures, myocarditis, metabolic syndrome
Parvovirus: pathophys and presentation
Erythrocyte precursors
Prodrome, followed by slapped cheek rash, progesses to lacy erythematous body rash
Length Constant
Length by which signals travel until intesnity is below a certain level
Mylenation effects on time and length constants
Increase Length, decreases time
Choriocarcinoma: gestational
Proliferation of cyto + sincytiotrophoblasts
Number Needed Formula
1/ (rate of incidence experimental - rate of incidence control)
Aortic Stenosis and Filling
LA compentation for LV hyptertrophy/loss of compliance (from stenosis)
Loss of LA leads to Acute Heart Failure
Pramipexole: MoA
Direct Stimulation of Dopamine Receptors
Broca and Wernicke’s bloody supply
Middle Cerebral Artery
Pancoast Syndrome: Presentation and Association
Shoulder Pain, Horner Syndrome, UE Edema, Spinal Cord Complications
Assocaited with smoking and hemoptysis (due to local tumor growth in Lung Apex)
Colchicine: MoA and Side Effects
MoA; microtubule formation inhibitor,
Side Effects: nausea, vomiting, diarrhea
Murmur intensity incerases
@ point with greatest pressure differential
Folate Deficiency: patho phys
Loss of dTMP synth leads to inhibition of nucleic acid synth
Obstructive Sleep Apnea: increased hematocrit pathophys
Decreased blood flow/oxygenation leads to increased erythropoetin, leading to increased hematocrit
