2/22/17

Question 1

Pancreatic Divisium: signs and pathophys

Answer 1

Signs: recurrent pancreatitis

Pathophys: failure of ventral and dorsal bud fusion, leading to twin ducts: Ventral and Dorsal(dominant) duct

Question 2

Pancreatic differentiation

Answer 2

Ventral: uncinate process, inferior/posterior head, major pancreatic duct

Dorsal: everything else

Question 3

Fidoxomicin: Use and MoA

Answer 3

Use: C. Diff infection

RNA Pol Inhibitor

Question 4

B-Blocker: MoA for HTN treatment

Answer 4

Block of Renin secretion leading to decrease in RAAS pathway

Question 5

Locations: Broca and Wernicke

Answer 5

Broca: Inferior Frontal Gyrus

Wernicke: caudal superior temporal gyrus

Question 6

Thiazide side effects

Answer 6

Hyper Ca, Hypo Na, HypoK, Metabolic Acidosis

Question 7

DM: Overflow incontience mechanism

Answer 7

Loss of detrusor contractibility due to neuropathy, leading to increased post void residual volume

Question 8

TTP and HUS: Common Symptoms

Answer 8

Platelet Activation, diffuse microvascular thrombosis, microangiopathic hemolytic anemia (with schistocytes) thrombocytopenia

Question 9

TTP-HUS: Classic Pentad

Answer 9

fever, neurosymptoms, renal failure, anemia, thrombocytopenia, in setting of GI illness

Question 10

Listeria: Growth Conditions

Answer 10

Can grow at refrigeration temperatures due to being an intracellular pathogen

Question 11

Clozapine: Side Effects

Answer 11

Aganulocytosis, seizures, myocarditis, metabolic syndrome

Question 12

Parvovirus: pathophys and presentation

Answer 12

Erythrocyte precursors

Prodrome, followed by slapped cheek rash, progesses to lacy erythematous body rash

Question 13

Length Constant

Answer 13

Length by which signals travel until intesnity is below a certain level

Question 14

Mylenation effects on time and length constants

Answer 14

Increase Length, decreases time

Question 15

Choriocarcinoma: gestational

Answer 15

Proliferation of cyto + sincytiotrophoblasts

Question 16

Number Needed Formula

Answer 16

1/ (rate of incidence experimental - rate of incidence control)

Question 17

Aortic Stenosis and Filling

Answer 17

LA compentation for LV hyptertrophy/loss of compliance (from stenosis)

Loss of LA leads to Acute Heart Failure

Question 18

Pramipexole: MoA

Answer 18

Direct Stimulation of Dopamine Receptors

Question 19

Broca and Wernicke’s bloody supply

Answer 19

Middle Cerebral Artery

Question 20

Pancoast Syndrome: Presentation and Association

Answer 20

Shoulder Pain, Horner Syndrome, UE Edema, Spinal Cord Complications

Assocaited with smoking and hemoptysis (due to local tumor growth in Lung Apex)

Question 21

Colchicine: MoA and Side Effects

Answer 21

MoA; microtubule formation inhibitor,

Side Effects: nausea, vomiting, diarrhea

Question 22

Murmur intensity incerases

Answer 22

@ point with greatest pressure differential

Question 23

Folate Deficiency: patho phys

Answer 23

Loss of dTMP synth leads to inhibition of nucleic acid synth

Question 24

Obstructive Sleep Apnea: increased hematocrit pathophys

Answer 24

Decreased blood flow/oxygenation leads to increased erythropoetin, leading to increased hematocrit

Question 25

Chronic Kidney Disease: Osteo Issues

Answer 25

Decrease in Vit D leads to increase in Phos, resulting in Increase PTH