2/28/17

Question 1

Pancreatic Adenocarcinoma: Signs and Symps

Answer 1

Nontender gallbladder, weight loss, obstructive jaundice (pale stool, dark urine, puritis)

Question 2

Chlorenphenicol: Side Effect

Answer 2

Grey baby

Question 3

Uncal herniation: Signs and Symps

Answer 3

Ipsilateral occulomotor nerve palsy (fixed dilated pupil)

Question 4

TE fistula/esophageal atresia vs Posterior nasal obstruction

Answer 4

Both: Cough, cyanosis

TE Only: Drooling

Question 5

Osteocyte communications

Answer 5

Gap Junctions

Question 6

Stop Codons

Answer 6

UAA
UAG
UGA

Question 7

Leukotriene B4: function

Answer 7

Most potent chemotaxis agent

Question 8

Lac Operon: Components

Answer 8

Single Promoter/repressor set, Single mRNA, multiple products

Question 9

IgA: Function

Answer 9

Inhibition of mucosal colonization due to attack of membrane or structural proteins

Question 10

Heparin MoA

Answer 10

Heparin binds Antithrombin, increasing Xa binding,

Bound Xa decreases prothrombin to thrombin conversion, leading to anticoag

Question 11

Radial vs Ulnar vs Medial nerve damage

Answer 11

Radial
Sign: wrist drop,
Sensory loss: posterior forearm, dosalateral hand
Weakness: Finger extensors

Ulnar:
Sensory: 1st and half of 2nd digit (medial side)
Motor: flexion of 4th/5th + wrist

Median:
Sensory: 1st 3 digits
Motor: thumb flexion/opposition, 1st/2nd digit flexion, wrist flexion, abduction

Question 12

Transesophageal echocardiogram: Heart positions

Answer 12

LA: Post posterior
LV: Lateral
RA: Anterior
RV: Lateral

Question 13

N. Gonorrhea: Immunity issues

Answer 13

Antigenic variability

Question 14

MS: bladder

Answer 14

Loss of inhibitory signaling > uncontrolled contraction of bladder

Question 15

Bosentan: MoA

Answer 15

Blocks endothelin (pulmonary vaso constrictors) leading to pulomonary vasodilation

Question 16

CD55 + CD59: Role and association

Answer 16

Complement inhibitors: associated paroxymal nocturnal hemoglobinuria

Question 17

Tertiary syphilis: Cardiac sequale

Answer 17

Aortic aneurysm (signs: aortic regurge + medialstinal widening)

Starts with vasa vasorum endarteritis

Question 18

First Gen Antipsychs: Side Effects

Answer 18

High Potency: extrapyramidal effects

Low Potency: sedation, anticholenergic

Question 19

Antiarrythmics: Side Effects

Answer 19

Orthostatic HTN

Question 20

Renal Hypoxic Damage: Most likely areas

Answer 20

proximal tubule + thick ascending loop

Question 21

Shaken Baby/abusive head trauma redflags

Answer 21

Retinal hemorrhage

Question 22

Liver Tests: AST/ALT vs PT/Albumin

Answer 22

AST/ALT: damage indicators

PT/Albumin: function indicators

Question 23

TB Drugs: Ethambutol side effects

Answer 23

Optic neuopathy