2D - Gene Expression Flashcards

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1
Q

precursor messenger RNA (pre-mRNA)

A

The immediate product of transcription of a DNA sequence. Requires modifications before it can undergo translation.

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2
Q

transcription factor

A

Proteins that bind to the promoter region and control the functioning of RNA polymerase.

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3
Q

template strand

A

The strand of DNA transcribed by RNA polymerase to produce a complimentary pre-mRNA strand.

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4
Q

coding strand

A

The strand of DNA NOT transcribed by RNA polymerase, contains an identical sequence to the mRNA strand produced (except thymine is replaced with uracil in mRNA).

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5
Q

ribosome

A

An organelle made of rRNA and protein that is the site of protein synthesis. Can be free in the cytosol or attached to the RER.

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6
Q

5’ methyl-G cap

A

A molecule added to the 5’ end of pre-mRNA during RNA processing.

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7
Q

3’ poly-A tail

A

A chain of adenine nucleotides added to the 3’ end of pre-mRNA during RNA processing.

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8
Q

splicing

A

process where introns are cut out of a pre-mRNA molecule, and exons are joined together.

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9
Q

spliceosome

A

The enzyme that removes introns from the pre-mRNA molecule and joins exons together during RNA processing.

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10
Q

alternative splicing

A

The process where different exons may be spliced, resulting in a single gene producing multiple different mRNA strands.

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11
Q

anticodon

A

The sequence of three nucleotides on a tRNA molecule that recognises a specific sequence of three nucleotides (codon) on an mRNA stand.

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12
Q

exocytosis

A

A type of bulk transport that moves large substances out of a cell.

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