2.5 Biological membranes Flashcards

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1
Q

What is a phospholipid bilayer made up of?

A
  • Hydrophilic Phosphate head

- Hydrophobic Fatty acids

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2
Q

What does hydrophilic mean?

A

Likes water

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3
Q

What does hydrophobic mean?

A

Doesn’t like water

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4
Q

What does partially permeable mean?

A

Allows some things to pass in and out however not others

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5
Q

What is simple diffusion?

A

The movement of molecules through a semi-permeable membrane where molecules move along a concentration gradient.

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6
Q

What molecules can simply diffuse?

A
  • Lipid soluble molecules
  • Non-polar molecules
  • Small molecules
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7
Q

What can’t simply diffuse through the membrane?

A
  • Charged molecules

- Large molecules

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8
Q

How do charged molecules move in and out of a cell?

A

Travel through carrier proteins

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9
Q

Why can small molecules pass through the membrane?

A

Can fit between phosphate lipid heads

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10
Q

Why can lipid soluble molecules pass through the membrane?

A

Dissolve into lipids and pass through

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11
Q

What is the role of membranes?

A
  • Separates cell components from external environments
  • Regulates transport of materials in/out of the cell
  • Might contain enzymes with specific metabolic pathways
  • Contains antigens so the immune system can recognise that the cell is it’s own
  • Releases chemical signals and contains receptors for cell communication
  • Site of Chemical reactions
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12
Q

Examples of membranes within the cell

A
  • mitochondria have folded inner membranes called Cristae so there is a larger surface area for aerobic respiration and localise enzymes that are needed for it
  • Inner membranes in chloroplast called thykaloid where photosynthesis reactions take place
  • Small intestine lining where digestive enzymes are on plasma membrane of epithelial cells which catalyse the break down of sugars
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13
Q

How is a concentration gradient maintained?

A

Molecules entering the cells pass to organelles for metabolic reactions (oxygen passes to the mitochondria)

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14
Q

Factors affecting diffusion

A
  • Temperature (more kinetic energy)
  • Diffusion distance (how thick the membrane is)
  • Surface Area (more space to diffuse through)
  • Size of molecules (smaller is faster)
  • Concentration gradient (steeper is faster)
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15
Q

What does polar mean?

A

Charged and can interact with water

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16
Q

What does Non-polar mean?

A

Can’t/won’t interact with water

17
Q

What passes through protein channels?

A

Charged molecules

18
Q

What passes through carrier proteins?

A

Large molecules

19
Q

What is the fluid mosaic model?

A
  • Proposed by Singer and Nicholson in 1972

- Membrane consists of a phospholipid bilayer with proteins floating in it

20
Q

Peripheral Proteins

A
  • don’t fully span phospholipid bilayer

- can act as an enzyme

21
Q

Phospholipid Bilayer

A
  • Phosphate head
  • Fatty acids
  • ‘main fabric’
22
Q

Integral Proteins

A
  • Spans phospholipid bilayer
  • Receptors
  • Channel proteins
  • Carrier proteins
23
Q

Glycoproteins

A
  • receptor
  • carbohydrate chain
  • attached to a lipid
  • glycocalyx with glycoproteins
24
Q

Cholesterol

A
  • Mechanical stability

- Improves flexibility/fluidity

25
Q

Factors of active transport

A
  • Moves against a concentration gradient
  • Needs ATP
  • Uses Carrier proteins
  • ATP and molecule binds to carrier proteins
26
Q

Factors of Endocytosis

A
  • How molecules are transported into a cell

- Segment of plasma membrane surrounds and encloses the particle

27
Q

What is Phagocytosis?

A

Intake of solid matter

28
Q

What is Pinocytosis

A

Ingestion of liquids

29
Q

What is exocytosis?

A
  • Large molecules exported out of the cell
  • Vesicle containing the molecule is transported towards the plasma membrane and fuses with it
  • ATP needed to fuse together