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2nd Year - Pathology > 2.05 Parasitic Infections > Flashcards

2.05 Parasitic Infections Flashcards

1
Q

Which specie of plasmodium causes benign form of malaria

A

P. Vivax, ovale, and malariae

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2
Q

Which species of plasmodium causes the severe form of malariae

A

P. Falciparum

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3
Q

What is the infective stage of plasmodium to man

A

Sporozoites

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4
Q

Diagnostic test for malaria

A

Blood smear

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5
Q

Malignant cerebral malaria is causes by

A

Plasmodium falciparum

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6
Q

Vector of malaria

A

Female anopheles mosquito

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7
Q

Causative agent of babesiosis

A

Babesia microti and B. divergens.

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8
Q

Histologic morphology of blood smear of patient with Babesiosis

A

resemble P. malaria ring stages but without hemozoin

Tetrads that form maltese crosses

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9
Q

Mode of transmission of Leishmaniasis

A

Bite of infected sandfly

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10
Q

Infective stage of Leshmania spp. to man

A

Promastigote

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11
Q

Infective stage of Leshmania spp. to sandfly

A

Amastigote

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12
Q

Virulence factor of promastigotes that promotes the adhesion of promastigotes to macrophages

A

Gp63

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13
Q

Causative agent of visceral Leishmaniasis

A

L. donvani

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14
Q

Presentation of visceral lieshmaniasis

A 
Hepatosplenomegaly
lymphadenopathy
pancytopenia
fever, myalgia, weight loss
hyperpigmentation of skin (Kala-azar)
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15
Q

Lesion in cutaneous lieshmaniasis

A

Tropical sore: Purple edematous plaque with central necrotic crust
Microscopic: granulomatous

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16
Q

Causative agent of mucocutaneous lieshmaniasis

A

L. brazilensis

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17
Q

Skin lesion in mucocutaneous lieshmaniasis

A

Espundia

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18
Q

Causative agent of African Trypanosomiasis

A

Trypanosoma gambiense and T.rhodesiense

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19
Q

African Trypanosomiasis is also known as

A

African Sleeping Sickness

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20
Q

Lesion in African Trypanosomiasis

A

Large, rubbery, red chancre at site of insect bite

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21
Q

The trypanosomes are found (inside or outside) the RBC

A

Outside the RBC

22
Q

Lieshmania is found (inside or outside) the RBC

A

Inside the RBC

23
Q

American Trypanosomiasis is also known as

A

Chagas Disease

24
Q

Causative agent of American Trypanosomiasis

A

Trypanosoma cruzi

25
Q

Skin lesion in American Trypanosomiasis

A

Chagoma

26
Q

Trypanosoma cruzi are transmitted via

A

Kissing bugs through their feces and non-intact skin

27
Q

Causative agent of strongyloidiasis

A

Strongyloides stercoralis

28
Q

Diagnostic tests for strongyloidiasis

A

Stool exam

Gastric lavage

29
Q

Causative agent of cystecerocis

A

Taneia solium

30
Q

MOT of cystecercosis

A

Ingestion of undercooked pork with cysterci

Ingestion of food or water contaminated with human feces

31
Q

Causative agent of Hydatid disease

A

Echinococcus granulosis

32
Q

MOT of causative agent of hydatid disease

A

Ingestion of food contaminated with eggs shed by dogs or foxes

33
Q

Hydatid disease most frequently invades the ___

A

Liver, aside from lungs and bones

34
Q

Causative agent of Trichinosis

A

Trichinella spiralis

35
Q

Mode of transmission of trichinella spiralis

A

Ingestion of undercooked meat from infected animals

36
Q

__ cells are muscle cells that have been parasitized by T. spiralis

A

Nurse cells

37
Q

S. japonicum is found in what part of the human host

A

Superior mesenteric vein

38
Q

S. mansoni is found in what part of the human host

A

inferior mesenteric vein

39
Q

S. hematobium is found in what part of the human host

A

Venous plexus of urinary bladder

40
Q

Liver cirrhosis in schistosomiasis is a result of

A

granuloma formation and fibrosis due to presence of eggs which elicit inflammatory responses

41
Q

Squamous cell carcinoma of the urinary bladder is associated with ___

A

S. hematobium

42
Q

S. hematobium infection presents with

A

hematuria and granulomatous disease of the urinary bladder (outlet obstruction)

43
Q

Causative agent of fliariasis

A

Wuchereria bacrofti and Brugia malayi

44
Q

Mosquito vector of Wuchereria bancrofti:

A

Culex, Anopheles, Mansonia & Coquillettidia

45
Q

Mosquito vector of Brugia malayi:

A

Culex, Mansonia, Anopheles

46
Q

Causative agent of Onchocerciasis

A

Onchocerca volvulus

47
Q

Onchocerciasis is transmitted via

A

the bite of black flies (Simullum sp)

48
Q

Important finding in onchocerciasis

A 
Chronic dermatitis (leopard, lizard, elephant skin)
Blindness
Subcutaneous nodule (onchocercoma)
49
Q

Babesiosis is transmitted via

A

Tick bite (deer tick)

50
Q

Transmitter of african sleeping sickness

A

Tse tse fly

2nd Year - Pathology (9 decks)

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