2.05 Fungal Infections

Question 1

Causative agent of candidiasis

Answer 1

Candida albicans

Question 2

Most frequent cause of human fungal infection

Answer 2

C. albicans

Question 3

Predisposing factors for developing candidiasis

Answer 3

Prolonged antibiotic therapy
Prolonged steroid administration
Pregnancy
Underlying disease
Altered immunity

Question 4

Candida albicans exists as a/an (intracellular/extracellular) parasite

Answer 4

Intracellular parasite

Question 5

Chronic mucocutaneous candidiasis is usually seen in patients with

Answer 5

Patients with defects in cell-mediated immunity

Question 6

Causative agent of Cryptococcosis

Answer 6

Cryptoccus neoformans

Question 7

Presentation of cryptococcosis in healthy individuals

Answer 7

Meningoencephalitis

Question 8

Presentation of cryptococcosis in immunocompromised individuals

Answer 8

Opportunistic infections

Question 9

The polysaccharid capsule of C. neoformans has ___ which inhibits phagocytosis, leukocyte migration & inflammatory cell recruitment

Answer 9

Glucoronoxylomannin

Question 10

Cryptococcus infects what organs

Answer 10

Lungs

CNS

Question 11

Most common pathogenic species for humans in Aspergillosis

Answer 11

Aspergillus fumigatus

Question 12

Infective stage of Aspergillus fumigatus

Answer 12

Conidia

Question 13

Aspergillus fumigatus can be isolated from )))

Answer 13

Nuts and grains and decaying matter, soil, and air

Question 14

Major portal of entry of A. fumigatus

Answer 14

Lung

Question 15

Pathologic findings in Aspergillosis

Answer 15

Acute/narrow angle branching
Septate hyphae
Angioinvasive
Fungus appears as a protein body in the upper respiratory tract

Question 16

Causative agent of Zygomycosis or Mucormycosis

Answer 16

bread mold fungi from the class Zygomycetes

Question 17

Primary sites of involvement in Zygomycosis

Answer 17

Nasal sinuses
Lungs
GIT

Question 18

Pathologic findgins in Zygomycosis

Answer 18

Broad, nonseptate hyphae
Right-angle branching
Angioinvasive

Question 19

Yeasts form at __ temperature

Answer 19

body temperature

Question 20

Molds form at ___ temperature

Answer 20

room temperature

Question 21

Most common fungal endocarditis

Answer 21

Candida albicans

Question 22

Cryptococcus neoformans is usually found in___ and infects people by __

Answer 22

Soil and bird droppings

Inhalation

Question 23

Virulence factor of crytococcus

Answer 23

Glucoronoxylomannin
Laccase
Serine proteinase
Basement membrane proteins

Question 24

Soap bubble lesions is found in __

Answer 24

cryptococcosis

Question 25

Aflatoxin is produced by

Answer 25

aspergillus fumigatus