1.03 - Fluid and Hemodynamics

Question 1

Function of the von willebrand factor (factor viii)

Answer 1

Platelet binding co-factor, bridge platelets together and with the endothelial cell; deficiency causes bleeding

Secreted by endothelial cell

Question 2

What are the significant differences between a postmortem and antemortem clot

Answer 2

Postmortem clots are formed only from clotting factors
Antemortem clots are formed from the contributions of endothelial blood vessel wall, platelets, and clotting factors (hence, the appearance of lines of Zahn)