2.03 Neoplasia

Question 1

What point mutation causes neoplasia?

Answer 1

Missense mutation

Question 2

Explain the philadelphia chromosome

Answer 2

The ABL gene goes to chromosome 22 and complexes with the bcr gene

The long part of the chromosome break in chromosome 22 transfers to the long arm of chromosome 9

Question 3

What is the first step to cellular change?

Answer 3

Cellular transformation

Question 4

The philadelphia chromosome is famous for which condition

Answer 4

Chronic myelogenous leukemia

Question 5

Chromosomes involved in burkitt lymphoma

Answer 5

Chromosome 8 and 14

Question 6

Gene involved in hereditary breast or ovarian cancers

Answer 6

BRCA1 and BRCA2

Question 7

The most commonly mutated gene in people with cancer is __

Answer 7

P53

Question 8

Syndrome of the deletion of one arm of p53 causing the development of multiple malignancies in one person

Answer 8

Li-Fraumeni Syndrome

Question 9

What is the most common carcinogen

Answer 9

Radon

Question 10

Enumerate the stop codons

Answer 10

UAG
UGA
UAA