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2nd Year - Pharmacology > 2.02 - Introduction To ANS > Flashcards

2.02 - Introduction To ANS Flashcards

1
Q

Nicotinic receptors ade mainly found in

A

Neuromuscular junctuin
Autonomic gangkia
Adrenal medulla

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2
Q

General effect of M1, M3, M5 receptors

A

Increase IP3 and DAG
Increased intracellular calcium
Muslce contraction, GIT wall contraction, outpouring of secretions of exocrine glands

EXCITATORY

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3
Q

General effect of M2 and M4 receptors

A

Parasympathetic will inhibit adenylyl cyclase, cAMP
Inceeased production of cGMP–> opening of K+ channels–>hyperpolarization

INHIBITORY

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4
Q

Muscarinic receptors are mainly found in

A

Heart
Smooth muscle
Exocrine glands

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5
Q

Action of botulinum toxin

A

Blocks exocytosis of Ach

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2nd Year - Pharmacology (18 decks)

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