2. NK Cells and YQ T Celss Flashcards

1
Q

How do NK Cells recognize their targets?

A

by the lack of MHC I

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2
Q

NK Cells are sensitive to…

A

Fc Receptors

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3
Q

What are the Activating receptors on NK Cells

A

NKG2D

CD16 (low affinity IgG Fc)

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4
Q

What are the Inhibiting receptors on NK Cells

A

NKG2A

KIR Family

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5
Q

What does KIR bind to?

A

MHC I

Detects healthy self tisue

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6
Q

What are 3 things that activate NK Cells?

A

Target cell
Leukocyte
Cytokines

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7
Q

Name 3 things of Innate activating NK Cells

A

2 signals
MHC surveillance
stress ligands

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8
Q

Name 2 things of Adaptive mechs Activate NK Cells.

A

Single Signal

Ig targeting

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9
Q

What is the role of yd T Cells?

A

remove diseased and malignant cells

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10
Q

What do CD1 express?

A

Self and

non-self lipids

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