2. Infectious Hepatitis Flashcards
What type of Hepatitis is acute?
A
B
E
What type of Hepatitis is Chronic?
B
C
Name some attributes of Acute Hep. (4)
Flue like symptoms
Jaundice
Elevated LFTs
Resolves spontaneously
Name some attributes of Chronic Hep. (3)
often asymptomatic
portal hypertension
LFTS are normal
Biology of Hep A. Virus
Non enveloped ssRNA virus
What is the transmision of Hep. A?
fecal oral
What is the most common cause of acute hep?
Hep A
When do you give the HEp A vaccine?
0 and 6-12 months
BIology of Hep E
no enveloped
ssRNA
How does Hep E spread
via fecal agua
Biology of Hep B?
Enveloped
DNA
dsDNA/ ssDNA
WHat is the smallest known human DNA virus?
Hep. B
IFN and nucleoside analogs are used for what virus?
Hep. B
Tenofovir and Entecavir are 1st in the US for?
Hep. B
What is the Biology of Hep D.
defective ssRNA
w/ a passanger HBV
How do you treat Hep D?
IFN alpha
What is the Biology of Hep C?
Enveloped RNA
Flavivirus
How do you transmit Hep C?
Blood
What does Hep C cause
cirrhosis and hepatocellular carcinoma
How do you test for Hep C? (probably not too important)
antibody immunoassay
molecular for HCV RNA
Who do you test for Hep C?
1945-1965
lots of stuff