1. Prostanoids & Anti-inflammatory Drugs Flashcards
What does NSAIDS do?
inhibit cyclooxygenase
What do Glucocorticoids do?
inhibit phopholipase A2
What does DMARDs do?
IDK but there is a biologic and traditional
What are Eicosanoids?
Oxygenatade unsaturated poly fats
Prostanoids are
a type of Eicosanoid
COX-1 or 2 not inhibit platelet aggregation or cause GI upsets?
COX-2
WHen would you not use Aspirin?
In children w/ viral induced illness (Reye syndrome)
What can inhibit both COXs in an irreversible manner?
ASA (aspirin)
what are some common NSAIDs?
Aspirin
ibuprofen
naproxen
Ibuprofen is derivative of
propionic acid
Is tylenol (Acetominophen) an anti-inflammatory?
no, no it is not so thus it isn’t a NSAID
What do Glucocorticoids target?
phospholipase A2
used for allergies
What are some Glucocorticoids?
Hydrocortisone
cortisone
prednisone
dexamethasone
What drug do you not use during pregnancy?
Methotrexate
