1. Pathology of Inflammation Flashcards
What are the major cells involved in acute inflammation?
Neutrophils, mononuclear cells, mast cell
What are the cells involved in chronic inflammation?
Mononuclear (Lymphocytes, Macrophages), fibroblasts
What causes chronic inflammation?
constant acute inflammation
and something about granulomatosis
What causes pain of inflammation?
PGE2, bradykinin, substance P and Histamine. That hang around free nerve endings
What are the Phases of Acute Inflammation?
- Vascular phase
2. Cellular Phase
What are the 4 movements in Cellular Phase?
Chemoattraction
Rolling
Adhesion
Transmigration
What is the predominant cell in acute inflamation?
neutrophil
Neutrophils adhere to which receptors? (2)
P
E
What does penia mean
less than normal
What does philia/cytosis mean?
more than normal
Leukocytosis w/ neutrophilia is….
acute inflammation
bacterial infection
Leukocytosis w/ lymphocytosis is….
chronic inflammation
viral infection
Eosinophilia is an indicator of…
parasitic infection, autoimune, allergies or type II
During infection can thrombocytosis occur?
yup sure can
increase of WBC is called a ___shift.
left
