19 Ass 10 immunity Flashcards

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1
Q

What are the functions of T- lymphocytes? 5

A

Production of cytokines

production of toxins

recognition of an antigen bound to an antigen-presenting cell

part of specific immune response

Can form memory cells

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2
Q

What are the functions of B lymphocytes? 3

A

Form plasma cells

can form memory cells

part of specific immune response

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3
Q

What is the function of plasma cells?

A

Secrete antibodies into blood plasmsa

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4
Q

What do T-helper cells do? 3

A

Release cytokines when activated

cytokines stimulate complimentary B-cells to divide quickly into plasma cells

cytokines can stimulate macrophages to ingest pathogen faster

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5
Q

What do T-Killer cells do?

A

Attach to complimentary antigens on antigen-presenting cell

release chemicals that kill host cell and pathogens inside

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6
Q

What cells engulf and digest pathogens? 3

A

Neutrophils
and Macrophages
(both are phagocytes)

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7
Q

Life cycle of T-lymphocyte 4

A

Produced in stem cells in bone marrow

mature in thymus gland

Constantly circulate body (mainly blood)

can leave blood and accumulate at sites of inflammation

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8
Q

life cycle of B lymphocyte

A

produced in stem cells in bone marrow

mature in bone marrow

leave bone marrow

constantly circulate in body (mainly blood)

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9
Q

Where are antibodies found during an immune response 2

A

In blood plasma

On the surface of cell membranes

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10
Q

What do memory cells do in long term immunity

A

Divide to form plasma cells and memory cells when pathogen enters body a second time

produce a fast response so that the person infected with pathogen doesn’t become ill again

remain in blood & lymphatic system after pathogen is destroyed

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11
Q

Do memory cells produce more antibodies than were produced during the primary immune response?

A

No

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12
Q

What is primary immune response?

A

When a host is infected for the first time with a new antigen

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13
Q

What is secondary immune response

A

When host is infected a second time with antigen and memory cells deal with it

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14
Q

6 what is E

A

B-memory cell

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15
Q

6 what is F

A

T-helper cell

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16
Q

6 What is G

A

T-killer cell

17
Q

6 what is H

A

plasma cell

18
Q

What is active immunity? 3

A

When a person goes through primary immune response

and activates B-lymphocytes to produce plasma and memory cells

leads to long-term immunity

19
Q

What are two was to acquire active immunity?

A

Be infected with new antigen for first time (natural)

Get vaccinated (artificial)

20
Q

What is passive immunity? 4

A

When antibodies aren’t produced by host but taken from another source

can be injected (artificial)

or drank in breast milk (natural)

only lasts a short time bc antibodies are broken down in body

21
Q

10 Read context and question

What blood group can be given to blood group B?

A

B and O

22
Q

What do macrophages do?

A

Recognise foreign antigens, go to them and engulf them

23
Q

What are monoclonal antibodies? 3

A

Specific antibodies produced by B-cells during clonal expansion and selection

Hard to produce in large quantities

high specificity means they’re used in medical diagnosis and treatment

24
Q

What is clonal expansion?

A

When B cells divide rapidly by mitosis

25
Q

13 read context and answer question

A

4 and 5 only

26
Q

14 read context and answer question

A

1,2 and 4

27
Q

Why doesn’t a one-does measles vaccination program work?

A

some children need several booster shots to develop full immunity

28
Q

How are monoclonal antibodies produced?

A

A mouse cell is injected with a sample of human fibrin protein

it develops an immune response that results in plasma cells in spleen

plasma cells collected and fused with a cancer cell to form a hybridoma

29
Q

Why are monoclonal antibodies so hard to produce

A

Plasma cells can’t divide by mitosis

30
Q

18 read context and answer question

A

B