16. Pharyngeal Arches Flashcards

1
Q

What week of development do the pharyngeal arches develop in?

A

4th/5th

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2
Q

What germ layer is found in the clefts?

A

Endoderm

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3
Q

What germ layer is found in the pouches?

A

Ectoderm

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4
Q

What is derived from the 1st pharyngeal arch?

A

Meckel’s cartilage

Malleus and incus

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5
Q

What is derived from the 2nd pharyngeal arch?

A

Stapes
Styloid process
Stylohyoid ligament
Lesser horn of hyoid

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6
Q

What is derived from the 3rd pharyngeal arch?

A

Greater horn of hyoid

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7
Q

What is derived from the 4th pharyngeal arch?

A

Upper thyroid cartilage

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8
Q

What happens to the 5th pharyngeal arch?

A

Disappears

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9
Q

What is derived from the 6th pharyngeal arch?

A

Rest of the thyroid cartilage

Cricoid cartilage

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10
Q

What is derived from the 1st pharyngeal cleft?

A

External acoustic meatus

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11
Q

What happens if the 2nd, 3rd and 4th clefts don’t disappear?

A

Cervical cysts

Presents as lumps under the sternocleidomastoid

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12
Q

What is it called if cervical cysts are open to the surface?

A

External branchial fistula

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13
Q

What do internal branchial fistulas open into?

A

Bed of palatine tonsils

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14
Q

What is derived from the 1st pharyngeal pouch?

A

Middle ear

Eustachian tube

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15
Q

What is derived from the 2nd pharyngeal pouch?

A

Palatine tonsils

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16
Q

What is derived from the 3rd pharyngeal pouch?

A

Inferior parathyroid

Thymus

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17
Q

What is derived from the 4th pharyngeal pouch?

A

Superior parathyroid

Ultimobranchial body

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18
Q

What does the ultimobranchial body become?

A

Parafollicular cells of the thyroid

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19
Q

What are 2 defects in the 1st arch?

A

Treacher Collins

Robin Sequence

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20
Q

What are the symptoms of Treacher Collins Syndrome?

A

Hypoplasia of maxilla, mandible and zygomatic arches

Associated with cleft palate and external ear defects

21
Q

What are the triad of conditions in Robin Sequence?

A

Micrognathia
Glossoptosis
Cleft palate

22
Q

What is micrognathia?

A

Poor growth of mandible

23
Q

What is glossoptosis?

A

Posteriorly placed tongue

24
Q

Name a syndrome of 3rd and 4th arch defects?

A

DiGeorge anomaly

25
What are the symptoms of DiGeorge anomaly?
No thymus or parathyroid glands Persistant truncus arteriosus Abnormal external ear Micrognathia
26
What is the innervation of the 1st arch?
Mandibular
27
What is the innervation of the 2nd arch?
Facial
28
What is the innervation of the 3rd arch?
Glossopharyngeal
29
What is the innervation of the 4th to 6th arches?
Vagus
30
What is the blood supply to the 1st arch?
Maxillary
31
What is the blood supply to the 3rd arch?
Common and internal carotids
32
What is the blood supply to the 4th arch?
Left: aortic arch Right: Subclavian
33
What is the blood supply to the 6th arch?
Left: Ductus arteriosis and left pulmonary Right: right pulmonary
34
What muscles arise from the 1st arch?
Muscles of mastication Mylohyoid Anterior digastric Tensor palati and tympani
35
What muscles arise from the 2nd arch?
Muscles of facial expression Posterior digastric Stylohyoid
36
Which parts of the tongue come from the 1st arch?
Lateral lingual swelling Medial swelling Tuberculum impar
37
Which parts of the tongue come from the 2nd, 3rd and 4th arches?
Copula
38
What does the epiglottis develop from?
Swelling from the 4th arch
39
What is behind the swelling of the epiglottis?
Laryngeal orifice | Arytenoid swellings
40
How is the anterior 2/3 of the tongue formed?
Lateral lingual swellings overgrow the tuberculum impar and merge
41
What separates the anterior 2/3 of the tongue from the posterior 1/3?
Terminal sulcus
42
Where does the thyroid develop?
Foramen cecum of tongue
43
What fuses to form the palate?
Intermaxillary segment | Maxillary processes
44
What are the issues with a cleft palate?
Food may go down the trachea | Nasal escape
45
What prominences make up the face?
Facial, maxillary, mandibular, frontonasal and nasal
46
How is the nose formed?
Maxillary processes grow medially Compress the nasal prominences in the midline Fuse together
47
What forms the upper lip?
2 medial nasal prominences | 2 maxillary prominences
48
What forms the lower lip and jaw?
Mandibular prominences