16. Pharyngeal Arches Flashcards
What week of development do the pharyngeal arches develop in?
4th/5th
What germ layer is found in the clefts?
Endoderm
What germ layer is found in the pouches?
Ectoderm
What is derived from the 1st pharyngeal arch?
Meckel’s cartilage
Malleus and incus
What is derived from the 2nd pharyngeal arch?
Stapes
Styloid process
Stylohyoid ligament
Lesser horn of hyoid
What is derived from the 3rd pharyngeal arch?
Greater horn of hyoid
What is derived from the 4th pharyngeal arch?
Upper thyroid cartilage
What happens to the 5th pharyngeal arch?
Disappears
What is derived from the 6th pharyngeal arch?
Rest of the thyroid cartilage
Cricoid cartilage
What is derived from the 1st pharyngeal cleft?
External acoustic meatus
What happens if the 2nd, 3rd and 4th clefts don’t disappear?
Cervical cysts
Presents as lumps under the sternocleidomastoid
What is it called if cervical cysts are open to the surface?
External branchial fistula
What do internal branchial fistulas open into?
Bed of palatine tonsils
What is derived from the 1st pharyngeal pouch?
Middle ear
Eustachian tube
What is derived from the 2nd pharyngeal pouch?
Palatine tonsils
What is derived from the 3rd pharyngeal pouch?
Inferior parathyroid
Thymus
What is derived from the 4th pharyngeal pouch?
Superior parathyroid
Ultimobranchial body
What does the ultimobranchial body become?
Parafollicular cells of the thyroid
What are 2 defects in the 1st arch?
Treacher Collins
Robin Sequence
What are the symptoms of Treacher Collins Syndrome?
Hypoplasia of maxilla, mandible and zygomatic arches
Associated with cleft palate and external ear defects
What are the triad of conditions in Robin Sequence?
Micrognathia
Glossoptosis
Cleft palate
What is micrognathia?
Poor growth of mandible
What is glossoptosis?
Posteriorly placed tongue
Name a syndrome of 3rd and 4th arch defects?
DiGeorge anomaly
What are the symptoms of DiGeorge anomaly?
No thymus or parathyroid glands
Persistant truncus arteriosus
Abnormal external ear
Micrognathia
What is the innervation of the 1st arch?
Mandibular
What is the innervation of the 2nd arch?
Facial
What is the innervation of the 3rd arch?
Glossopharyngeal
What is the innervation of the 4th to 6th arches?
Vagus
What is the blood supply to the 1st arch?
Maxillary
What is the blood supply to the 3rd arch?
Common and internal carotids
What is the blood supply to the 4th arch?
Left: aortic arch
Right: Subclavian
What is the blood supply to the 6th arch?
Left: Ductus arteriosis and left pulmonary
Right: right pulmonary
What muscles arise from the 1st arch?
Muscles of mastication
Mylohyoid
Anterior digastric
Tensor palati and tympani
What muscles arise from the 2nd arch?
Muscles of facial expression
Posterior digastric
Stylohyoid
Which parts of the tongue come from the 1st arch?
Lateral lingual swelling
Medial swelling
Tuberculum impar
Which parts of the tongue come from the 2nd, 3rd and 4th arches?
Copula
What does the epiglottis develop from?
Swelling from the 4th arch
What is behind the swelling of the epiglottis?
Laryngeal orifice
Arytenoid swellings
How is the anterior 2/3 of the tongue formed?
Lateral lingual swellings overgrow the tuberculum impar and merge
What separates the anterior 2/3 of the tongue from the posterior 1/3?
Terminal sulcus
Where does the thyroid develop?
Foramen cecum of tongue
What fuses to form the palate?
Intermaxillary segment
Maxillary processes
What are the issues with a cleft palate?
Food may go down the trachea
Nasal escape
What prominences make up the face?
Facial, maxillary, mandibular, frontonasal and nasal
How is the nose formed?
Maxillary processes grow medially
Compress the nasal prominences in the midline
Fuse together
What forms the upper lip?
2 medial nasal prominences
2 maxillary prominences
What forms the lower lip and jaw?
Mandibular prominences