16: Gene Expression Flashcards
3’ untranslated region; region just downstream of the protein-coding region in an RNA molecule that is not translated
3’ UTR
a methylated guanosine triphosphate (GTP) molecule that is attached to the 5’ end of a messenger RNA to protect the end from degradation
5’ cap
5’ untranslated region; region just upstream of the protein-coding region in an RNA molecule that is not translated
5’ UTR
protein that binds to prokaryotic operators to increase transcription
activator
protein that complexes with cAMP to bind to the promoter sequences of operons which control sugar processing when glucose is not available
catabolite activator protein (CAP)
transcription factor binding sites within the promoter that regulate the transcription of a gene adjacent to it
cis-acting element
enzyme that chops the pre-miRNA into the mature form of the miRNA
Dicer
epigenetic modification that leads to gene silencing; a process involving adding a methyl group to the DNA molecule
DNA methylation
segment of DNA that is upstream, downstream, perhaps thousands of nucleotides away, or on another chromosome that influence the transcription of a specific gene
enhancer
heritable changes that do not involve changes in the DNA sequence
epigenetic
protein that binds first to an mRNA to initiate translation
eukaryotic initiation factor-2 (eIF-2)
processes that control the turning on or turning off of a gene
gene expression
molecule that is left after the energy is used to start translation
guanine diphosphate (GDP)
energy-providing molecule that binds to eIF-2 and is needed for translation
guanine triphosphate (GTP)
epigenetic modification that leads to gene silencing; a process involving adding or removing an acetyl functional group
histone acetylation
operon that can be activated or repressed depending on cellular needs and the surrounding environment
inducible operon