15 - chronic abdominal pain Flashcards

1
Q

Welcome to week 14

A

https://youtu.be/dQw4w9WgXcQ

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2
Q

What is the ROME criteria

A

Used to diagnose functional gut disorders like IBS

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3
Q

Symptoms of IBS

A

Abdo pain - colicky

Bloating

altered bowel habit

Greater than 6 months

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4
Q

What are red flags for abdominal pain?

A

> 60 years

rectal bleeds

anaemia

weight loss

FH of colorectal cancer

Abdo/ rectal mass

Raised CRP/ESR

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5
Q

What dietary advice should be given to patients suffering from IBS?

A

Avoid fermentable carbohydrates - fructose lactose

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6
Q

What is Carnett’s sign?

A

Abdominal pain made worse on the site of palpation when a patient sits up.

If positive then pain is from the abdominal wall rather than the viscera.

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7
Q

What is loperamide?

A

Opioid agonist which focuses on the mesenteric plexus.

Used for diarrhoea

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8
Q

What is linaclotide?

A

Used for constipation (via CFTR) for constipatino > 12 months when laxatives dont work.

Used 2nd line (by definition) in IBS

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9
Q

When can you initiate psychological therapy for IBS (NICE guildlines)?

A

> 12 months of suffering from IBS whith it not getting better

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10
Q

How is ulcerative collitis diagnosed?

A

> 4 weeks of diarrhoea with evidence of acute and chronic inlfammation on endoscopic and biopsy

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11
Q

How is Crohns disease diagnosed?

A

endoscopic evidence and imaging with compatible clinical history

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12
Q

What is tenesmus?

A

Repeated need to empty bowels

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13
Q

What is the definition of diarrhoea?

A

Greater than 2 unformed stools per day

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14
Q

What is disentry?

A

Diarrhoea with blood in it

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15
Q

What is acute diarrhoae?

A

Diarrhoea lasting less than 4 weeks

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16
Q

What is chronic diarrhoea?

A

Diarrhoea lasting greater than 4 weeks

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17
Q

Having antibiotics for greater than 1 months increases the risk of diarrheoa due to…

A

Clostridium deficile

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18
Q

What is calportectin?

A

Indicates if there is any underlying inflammation in the GI tract. If negative would help to support a diagnosis of IBS

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19
Q

Is smoking protective or harmful with Crohns?

A

Smoking is harmful, smoking cessation should be part of the treatment for Crohns.

20
Q

Is smoking protective or harmful with Ulcerative Collitis?

A

Smoking is protective with ulcerative colitis

21
Q

What features of Ulcerative collitis are present on endoscopy?

A

Continoues erthematous inflammation with pseudo polyps.

22
Q

What features of Crohns are during endoscopy?

A

Skipp lesions with a cobblestone appearence

23
Q

What complications can occur due to Crohns?

A

Stenosis

Abcess

Fistula and performation

Increase rate of colorectal cancer

24
Q

What complications can occur due to Ulcerative collitis?

A

Bleeds

Toxic megacolon

Ruptured bowel

increase risk of colorectal cancer

25
Q

When can you no longer take stool cultures from a patient in hospital?

A

Stool samples should ont be takem after 3 days.

26
Q

What is the commonest cause of gastroeneteritis in the UK?

A

Campylobacter

27
Q

What is HUS?

A

Haemolytic urea syndrome, caused by a strain of E. coli and shigella dysentry

28
Q

What is TTP?

A

thrombolytic thrombocytopenia purpura. Low platelet count caused by with many causes inculuding E.coli

29
Q

Patient has rice water stool after coming from abroad. What is the cause?

A

Cholera

30
Q

What is Giadrasis?

A

A parasite which can cause chronic diarrhoea

31
Q

What is the red flag for ovarian cancer?

A

Female over 50 with bloating.

32
Q

What does Ca125 indicate?

A

Marker for ovarian cancer

33
Q

What is the true witts criteria?

A

A way of measuring the severity of IBD

34
Q

Would be safe to do a colonoscopy during a flare up of US or Crohns?

A

NO due to risk of perforation, possibly flexible sigmoidoscopy

35
Q

What is the definition of a fistula?

A

Abnormal connection between to 2 epithelial linings

36
Q

When treating IBD TB should be excluded. How is TB tested for?

A

Quantifieron

37
Q

UC is limited to the large bowel, how can it effect the small bowel?

A

Backwash ileuitis

38
Q

What is the gold standard investigation for crohns?

A

Pilcam - a camera as a pil

39
Q

What is the MUST score?

A

Greater than 2 indicates malnutrition

40
Q

What is refeeding syndrome?

A

Fedding after MI which causes MI, due to washing over electrolytes over the cardiac tissue.

41
Q

What condition are 5-ASA drugs like mesalazine used for?

A

Ulcerative collitis and not Crohns

42
Q

What is first line for Crohn’s?

A

Azathiopurine or mertaptopurine

These can also be used for UC after mesalazine

43
Q

What medicaiton is second line for Crohn’s disease?

A

Metotrexate

44
Q

After 4 weeks of a flare up of UC. What mediation can be used to induce remission?

A

Glucocorticoids

45
Q

What can be used for inducing remision of Crohns after a flare up?

A

1st glucocorticoids

2nd 5-ASA and 1st line therapy

46
Q
A