14 - Genetic Eng, Therapy, Down Syndrome

Question 1

Gene manipulation

Answer 1

removing defective gene, replace with a normal one to reduce risk of genetic defect in newborns

Question 2

Genetic therapy

Answer 2

the introduction of genes into multicellular plants and animals sometimes by means of a harmless vurus

Question 3

Two main approaches of gene therapy

Answer 3

• transferred genes replace defective
• selectively inhibit harmful genes

Question 4

Issues with gene therapy

Answer 4

• genetically modified plants and animals for human consumption
• access of genetic information > insurance companies

Question 5

Genetic engineering

Answer 5

manipulating nucleic acids + recombining genes into hybrid molecules that can be inserted into unicellular organisms and reproduces several times over

Question 6

Each hybrid molecule produces

Answer 6

clones, genetically identical

Question 7

Human genome project has determined

Answer 7

millions of base pairs in human DNA strand

Question 8

Trisomy (Down Syndrome/Trisomy 21)

Answer 8

presence of an additional third chromosome

Question 9

Down Syndrome Effects

Answer 9

• slanting eyes
• flat facial profile
• bridge palmar crease
• widened space between toes
• shortened 5th digit

Question 10

Cause of Down Syndrome

Answer 10

error in cell division during meiosis

Question 11

DS prenatal testing

Answer 11

• triple screen (AFP, hGC, unconjugated estriol)
• maternal blood test at 15-20wks
• fetal nuchal translucency
• amniocentesis
• chorionic villus sampling
• PUBS