12.5 Non-specific defences against pathogens Flashcards

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1
Q

what is faster specific or non-specific defence?

A

non-specific

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2
Q

examples of barriers the body has to pathogens

A

skin
membranes
organelles

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3
Q

skin

A

skin produces sebum to prevent growth of pathogens

contains healthy microorganisms which outcompete the pathogenic microorganisms

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4
Q

membranes

A

mucous membranes secrete mucus which traps pathogens and microorganisms
mucus contains lysosomes and phagocytes which are used ti destroy the pathogen being trapped

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5
Q

organs

A

lysosomes are found in tears and urine
acid in the stomach

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6
Q

describe how blood clotting occurs?

A

tissue is damaged
thromboplastin and serotonin are released
thromboplastin leads to the production of thrombin
thrombin catalyses the conversion of fibrinogen to fibrin
fibrin hardens to form a clot

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7
Q

what does serotonin do?

A

causes smooth muscle in blood vessels to contract which narrows the lumen and reduces blood supply to the damaged area

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8
Q

what is activated when inflammation occurs?

A

mast cells

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9
Q

what do mast cells release?

A

histamines and cytokines

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10
Q

role of histamines?

A

causes blood vessels to dilate which increases the temperature to prevent pathogens from reproducing

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11
Q

role of cytokines?

A

attract phagocytes and allow for phagocytosis of pathogens to occur

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