12.5 Non-specific defences against pathogens Flashcards
what is faster specific or non-specific defence?
non-specific
examples of barriers the body has to pathogens
skin
membranes
organelles
skin
skin produces sebum to prevent growth of pathogens
contains healthy microorganisms which outcompete the pathogenic microorganisms
membranes
mucous membranes secrete mucus which traps pathogens and microorganisms
mucus contains lysosomes and phagocytes which are used ti destroy the pathogen being trapped
organs
lysosomes are found in tears and urine
acid in the stomach
describe how blood clotting occurs?
tissue is damaged
thromboplastin and serotonin are released
thromboplastin leads to the production of thrombin
thrombin catalyses the conversion of fibrinogen to fibrin
fibrin hardens to form a clot
what does serotonin do?
causes smooth muscle in blood vessels to contract which narrows the lumen and reduces blood supply to the damaged area
what is activated when inflammation occurs?
mast cells
what do mast cells release?
histamines and cytokines
role of histamines?
causes blood vessels to dilate which increases the temperature to prevent pathogens from reproducing
role of cytokines?
attract phagocytes and allow for phagocytosis of pathogens to occur