1.2.11 Mutations

Question 1

What is an example of a mutation occurring?

Answer 1

An example of a gene mutation is an incorrect base slipping into place

Question 2

What may happen if a mutation form in the ovaries or testis?

Answer 2

If a mutation forms in the ovaries or testis, the mutation may be passed on to future generations

Question 3

What may happen if a protein is formed faulty?

Answer 3

If a protein is formed faulty, it may lead to a genetic disorder

Question 4

Describe what happens in sickle cell anaemia

Answer 4

There is a mutation in the gene that codes for a polypeptide in haemoglobin. The mRNA is produced with the wrong bases, making it less soluble. The shape then becomes distorted, meaning it can carry less oxygen.

Question 5

How does a mutation affect the CFTR protein?

Answer 5

ATP is unable to bind and open the ion channel, meaning there is less movement of the chloride ion.