12. Immunologic and Hematological Systems Flashcards

1
Q

Myel-

A

Bone Marrow

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2
Q

-poiesis

A

Formation; production

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3
Q

Composition of blood

A

55% Plasma
41% Red Blood Cells
4% White Blood Cells and Platelets

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4
Q

Plasma

A

90% water
10% dissolved salts, nutrients albumin clotting factor, wasts, etc.

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5
Q

CIDP

A

Chronic inflammatory demyelinating polyneuropathy - causes weakening in arms and legs leading to possible paralysis.

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6
Q

Hemophilia A is:

A

A genetic bleeding disorder cause by lack of protein factor VIII

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7
Q

Hemophelia B is:

A

Genetic bleeding disorder caused by lack of protein IX

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8
Q

Von Willebrand disease

A

Disorder in which the blood does not clot properly.

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9
Q

Hematopoiesis is

A

Blood Production

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10
Q

Erythocytes

A

Red Blood cells - carry oxygen from the lungs to cells and carbon dioxide back to be exhaled. Last for 120 days

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11
Q

Thrombocytes

A

Platelets; form blood clots by coagulation

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12
Q

Hemostasis

A

Stop bleeding

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13
Q

Healthy Platelet count

A

150-450,000 platelets per microliter

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14
Q

Thrombocytosis

A

Having too many platelets

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15
Q

Thrombocytopenia

A

Having too few platelets

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16
Q

Fibrin

A

Thread-like structure that forms the external clot or scab

17
Q

Megakaryocytes

A

Formed in the blood marrow. Fragments are platelets.

18
Q

Granulocytes

A

Neutrophils
Eosinophils
Basophils

19
Q

Neutrophils

A

First line of defense; identifies the site of infection and ingests microorganisms, releasing enzymes to destroy them.

20
Q

Eosinophils

A

Combat parasitic infection and are inolved in some allergic reactions and cancers

21
Q

Basophils

A

Least common; release enzymes to dilate blood vessels when an allergen is identified in an attempt to flush the allergen out.

22
Q

Enzymes released by basophils

A

Histamine and heparin

23
Q

Agranulocytes

A

Monocytes
Lymphocytes

24
Q

Monocytes

A

Stored in bone marrow and last 24 hours. When released they mature into macrophages, which engulf infected cells and ingest them.

25
Q

(2) types of Lymphocytes

A

B-Cell
T-Cell

26
Q

B-Cell Lymphocytes function

A

Rapidly multiply, forming plasma cells and antibody proteins also known as immunoglobulins. Can be trained via vaccinations.

27
Q

T-cell lymphocytes

A

Originate in the marrow but mature in the thymus gland.

28
Q

Types of T-cell lymphocytes

A

Helper T-cells: Produce cytokine to stimulate the formation of antibodies

Regulatory T-cells: Control immune reactions to prevent over-activity

Cytotoxic T-cells: Activated by cytokine, kill foreign cells, infected cells and cancer cells

29
Q

Specific Immunity

A

Born with and acquired over a lifetime as the body is exposed to the environment or passively through vaccination

30
Q

Non-specific Immunity

A

Comprised of physical barriers or chemical defenses

31
Q

(3) types of Phagocytes

A

Neutrophils, monocytes, and macrophages

32
Q

CIPD

A

Chronic Inflammatory Demyelinating Polyneuropathy - nerve disorder causing weakness and numbness in harms and legs.