119 Mod 5 Endocrine, EENT, Peds, Immuno Flashcards
What is utcaria
Hives, allergic reaction
Define Thyrotoxicosis
what falls under this category?
is a state of EXCESSIVE THYROID hormone production or release. Signs include weight loss, rapid heartbeat, tremors, sweating
(NOTE: grave’s disease falls under this)
it is any condition with excessive thyroid hormone
When are leukotrienes release?
They are released AFTER histamine worsens anaphylaxis increases Bronchoconstriction
They are molecules produced by immune cells, play a key role in inflammatory response of the body, because constriction of the airways increase mucus production, inflammation and recruitment of immune cells due to an allergen or irritant
Define:
Polyphagia
Polydipsia
Polyuria
can occur with?
Excessive hunger
Excessive Thirst
Excessive peeing
poorly managed diabeties
Other than hearing what key role does the ear play
Maintain balance
Why what is Myxedema coma
And what are the signs
is a life-threatening complication of SEVERE HYPOTHYROIDISM, leading to altered mental status, hypothermia, and multiorgan dysfunction.
Patient is optunded (AMS), cold to the touch, bradycardic
True or false there’s an oral medication for type 1 diabetes
False there’s no oral insulin
IDDM stands for
“Insulin-Dependent Diabetes Mellitus,” which is an older term for Type 1 Diabetes.
Type 1 Diabetes is usually diagnosed in children and young adults
In Type 1 Diabetes, the pancreas produces little or no insulin, while in Type 2 Diabetes, the body becomes resistant to insulin or doesn’t produce enough insulin.
What are the key differences between type 1 and type 2 diabetes
Type 1 is usually diagnosed in children
Type 2 is usually diagnosed in adults over the age of 40
Type 1 the the pancreas produces little to no insulin
Type 2 the body becomes resistant to insulin or doesn’t produce enough
signs:
Type 1 - excessive thirst, frequent urination unexplained weight loss and fatigue
Type 2 - blurred vision numbness tingling in the hands and feet, similar signs
When bacteria die inside of a body they release a protein that is called an
Endotoxin
Which is subnormal T3 and T4 production a sign of
Hypothyroid
Low thyroid = low, slow, cold
Define Anaphylactoid Reaction
allergic reaction after 1st time exposure to substance. (Not IgE mediated.) Same clinical picture as anaphylaxis so they are treated the same
The ________ is a large part of the endocrine system, but it is not an actual gland
Hypothalamus
What is the dose of Atrovent?
what class?
500mcg
anticholinergic bronhchodilator
half if 1-2 years old
do not give less than 1
Gland but important essential, bodily functions, such as temperature, hunger thirst and hormone secretion
Hypothalamus
What does the Alpha receptors in the pancreas secrete
and what does it do?
Glucagon
it is released when BGL is LOW to
stimulate the live to turn glucogen to sugar
What is the difference between HHNK and DKA?
DKA -shortage of insulin, fats breakdown body starts ketone production, metabolic acidosis, (blood too acidic) fruity smelling, nausea, ab pain
HHNK involves severe dehydration without ketone production. Theres enough insulin but not enough to lower bgl
extreme thirst, dry mouth, dry skin
DKA is considered more serious due to metabolic acidosis
The BREAKING DOWN of glycogen to the usable form of glucose is termed ________ (INTO A SINGLE)
Glycogenolysis
What is the difference between diabetes insipidus and diabetes mellitus
Diabetes insipidus is caused by not enough ADH hormone, (pituitary disorder)
while diabetes mellitus is caused by insulin deficiency or resistance.
Buffalo hump, Moon face and acne as signs of?
and what is the cause
Cushing syndrome
excess cortisol hormone
What happens if no ADH is produced
Increased urine production occurs
What are the signs of Cushing syndrome (big 2 signs)
What is Cushing syndrome
What is the treatment of Cushing syndrome
Signs are moon face, buffalo hump, diagnosed with fibromyalgia, unusual hair growth
its is a disorder caused by EXCESS CORTISOL secretion, often due to pituitary or adrenal gland tumors. Too much corticosteroids
supportive care
In times of stress how does the hypothalamus respond
What does the response cause
secretes ACTH
then the adrenal cortex releases CORTISOL
Cortisol stimulates fight or flight
ACTH (adrenocorticotropic hormone) is a hormone produced by the anterior pituitary gland that stimulates the adrenal glands to produce cortisol and other steroid hormones.
Immunity you are born with is called
Innate/natural immunity
Hypertension and Bradycardia in a unconscious patient indicates?
ICP
Increases (Stimulates) production and secretion of thyroid hormones
TSH
Thyroid stimulating hormone
Produced by the pituitary gland
What is it called when our body creates “autoantibodies” and attacks its own tissues?
autoimmunity
Your patient had a sinkable episode and now has SOB, face swelling, and abdominal pain
You suspect ______ and why
Anaphylaxis
Because it’s two or more body systems
The thymus gland is located in the ________
Chest
Mediastinum
What is an endocrine gland
Give three examples
Secretes chemicals that are used INSIDE the body
Adrenal
Pituitary
Thyroid
T3 T4 and calcitonin (hormones) are produced by the _______ gland
Thyroid
What might cold and clammy skin indicate
hypothyroidism (also cold/dry)
hypoglycemia
(shock or hypothermia)
For women progesterone production and ovulation
For men it regulates testosterone production and spermogenesis
LH
LH (luteinizing hormone) is a hormone produced by the pituitary gland that stimulates ovulation in females and testosterone production in males.
The female gonads are found in the ________
The two most important hormones produced by the female gonads are ________ and ________
Ovaries
Estrogen and progesterone
What are the 4 adrenal gland disorders
(2 have same name…)
Cushings Syndrome – too much corticosteroids (cortisol and aldosterone)
Addison’s Disease – too little corticosteroids
Addisonian Crisis – extreme exacerbation of low corticosteroids
PheoChromocytoma – tumor creating excess release of Catecholamines
Where is melatonin produced
Pineal gland
What are the properties of Epinephrine
(what is it doing)
Alpha 1 agonist
B1 and B2 agonist
halts degranulation of mast cells
What is ADdisonian Crisis
what can cause it?
Acute ADrenal (low) insufficiency
from stress, surgery, trauma, or infection
hyponatremia (low sodium) leading to hypotension
can be from corticosteroid steroid withdrawal
With the adrenal gland:
what is disorder for:
LOW cortisol
Addison’s Disease
In the body’s attempt to maintain_________ it utilizes________ and_______ feedback mechanisms
Homeostasis
Positive
Negative
Would you give a patient in bradycardia
When pacing an atropine don’t work
And dose (2)
Dopamine 2 -10 mcg/kg/min
Epi 2-10 mcg/min
(or both)
The endocrine system is a network of________- that produce and secrete______
Which are chemical Messengers
Glands
Hormones
What is the treatment for an impaled eye?
cover with gauze, cover both eyes
What is an exocrine gland
Name three examples
It secretes chemicals for elimination FROM the body
sweat glands
salivary glands
the liver
Define Congenital Adrenal Hyperplasia
it is an adrenal gland disorder
causing low cortisol and high androgens
signs are early onset of puberty, In females, signs of CAH include ambiguous genitalia, irrg periods
(signs are more noticeable in women)
Where is calcitonin produced
Thyroid gland
The ________ is both an endocrine and exocrine gland
Pancreas
After an organ transplant your patient is red and warm with edema
What might be happening
Transplant rejection
What two things happen during histamine release
Increase vascular permeability
Bronchoconstriction
What is hypothyroidism
What are the signs
And what is the medication treatment
It’s when the thyroid gland produces not enough thyroid hormone,
causing decreased metabolism.
Cold skin, and weak
Synthroid or levoxyl
Thymosin (hormone) is produced by the ________ gland
Thymus
Thymosin is a hormone produced by the thymus gland that plays a role in the development and maturation of T-cells.
T cells are a type of white blood cell that play a central role in cell-mediated immunity and in coordinating the immune response.
Stimulates milk production
Prolactin
Pale cool moist skin maybe be a sign of? (2)
Shock
Hypoglycemia
Endocrine emergencies are generally caused by (3)
Lack of hormone production
Excessive hormone production
Failure of feedback mechanism
what is the dose of an EPI drip
how do you set up?
How many drops a min?
1mg in 100mL at 60gtts/min
after 5 mins 120gtts/min
1mg in to a 100mL bag
10 y/o F ate a peanut, doesnt have her prescribed epi-pen. Has SOB dysphaGia, Wheezing
what is the treatment?
Epi - 1:1,000 - 0.5mg x3
Neb treatment
dysphagia - difficult swallowing
dysphaSIA- speaking
Hot and Dry skin maybe a sign of? (3)
Fever
Hyperglycemia
or Stoke
(give fluids)
Glucagon is produced in the ________
Pancreas
Converts glycogen into the usable form of glucose
Glucagon
Insulin lowers blood glucose levels by promoting glucose uptake and storage,
glucagon raises glucose levels by stimulating glycogenolysis and gluconeogenesis.
What does the D receptors in the pancreas secrete
Somastatin
Which Receptor sites does epinephrine affect
Alpha receptor sites
Controls plasma osmolarity and increases water reabsorption
ADH - antidiuretic hormone
What is the
adult dose of epi
And pediatric dose
Adult
0.3 -0.5 mg 1 : 1,000 IM
Pediatric
0.01 mg/kg 1 : 1,000 IM
2-10mcg/min infusion
What is DKA
What are the signs of dka
What is the treatment for dka
What bgl amount?
Extreme hyperglycemia, ketosis, and metabolic acidosis.
Type 1 diabetics are at risk
signs: polyuria, polydipsia, abdominal pain, fruity breath, Kussmaul breathing, AMS, and dehydration.
Fluids, patient needs insulin from the hospital needs insulin to utilize the glucose (hyperglycemia)
Peds - fluids when in SHOCK
Often above 300 bgl (mg/dl)
Which endocrine gland is also known as the master gland
Why
The pituitary gland
It’s secretions control the secretions of all the other endocrine glands
What are the two HYPERthyroidism dangers (2)
what are the signs of them
Graves disease - bulging eyes = exophthalmos ( most common)
Thyroid storm - heart rate up respirations up temperature up, CHF (may follow thyroid surgery)
Hyper = High hot fast
Liver stores glucose in the form of ________
What is the process called
Glycogen
Glycogenesis
What is the IM dose of glucagon (max?)
when do you give
and what type of overdose?
1mg IM (or IV) max of 3mg
hypoglycemic or beta blocker overdose
Everyday autism care
Develop and language skills
89 y/o Black F taking lisinopril (ace inhib) and for 4 days swollen face but can swallow.
what is the treatment?
Angioedema
Steroids needed
but can do allergic reaction protocol
What type of cell produces insulin
and what are the primary effects of insulin on the body
Beta Cells
Islet of langerhands
in the Pancreas
Insulin regulates glucose metabolism after a meal. It goes in the blood stream and allows the body to take glucose to the muscles fat and liver cells. And helps with storage of glucose as glycogen.
When do most infants suffer SIDS?
most are during the first 6 mos
most have both lividity (obvious sign, purple) and rigor mortis
allow parents to touch
use baby’s name
Define Angioedema
rapid swelling of the skin’s deeper layers, usually in the face, lips, tongue, or throat. Potentially life threatening
Prehospital anaphylaxis
Stimulates development of T cells
Thymosin
is a hormone produced by the thymus gland that plays a role in the development and maturation of T-cells.
T cells are a type of white blood cell that play a central role in cell-mediated immunity and in coordinating the immune response.
After an organ transplant the patient has red warm edema
what is happening
Transplant rejection
Urticaria vs Pruritis
Urticaria - hives
PrurITIS - iching
What is the IV/IM dose of Diphenhydramine
when do you give
what is the PED dose?
Adult: 25-50mg SLOW IV/IM
Ped: 1mg/kg SLOW IV/IM
anaphylaxis, allergic reaction
In the setting of pediatric pulses arrests, what anti arrhythmic medication (including dose) can be given to a patient in v-fib (2)
Amiodarone
Pediatric dose 5 mg/kg
Or
Lidocaine 1 mg/kg
Define Angioedema
swelling of deep tissues of face due to accumulation of fluids. (Hives/Urticaria involve the epidermis while angioedema affects deep dermal, sub-Q and sub-mucosal layers. Predominantly around the mouth, lips, tongue, eyes (may also be present in hands, feet, and throat).
ACE inhibitors are the leading cause of drug induced angioedema!
The formation of glucose from non-carbohydrate forms is termed ________
Gluconeogenesis
You find uticaria and your patient’s abdomen, you should administer
(and dose, adult and ped)
Diphenhydramine 25-50 mg
ped 1-2mg/kg (max 50mg)
Check for ABC and DE
what does D and E stand for?
D - disability
E - exposure
airway breathing circulation
For women estrogen production and follicle maturation
For men spermogenesis
FSH
FSH (follicle-stimulating hormone) is a hormone produced by the pituitary gland that stimulates the growth and maturation of ovarian follicles in females and sperm production in males.
Sleep wake pattern and mating behavior
Melatonin
Which cranial nerve is
oculomotor
and
optic
oculomotor - 3rd
optic - 2nd