119 Mod 3 (Cardiology and Peds) Flashcards
Name 2 analgesics
nitroglycerine
narcotics - opioid/fentnyl
Dopamine dose
2-20mcg/kg/min
When do we use fentanyl?
pain management
What type of drug is ASA?
Anti-platelet
What class is Nitroglycerin?
Nitrate
Left Sided Heart Failure, what happens, what is treatment
** causes fluid backup in the lungs
- usually due to MI, infection, or valvular diesease
- our goal is to increase oxygenation, decrease workload of heart
Tx: )2, CPAP, nitrates, morphine
Define Thrombus vs embolus
thrombus is a mass of blood constituents; stationary, attaches to vessel wall
an embolus is a floating clot that can lodge anywhere…can be air, fluid, bone, fat, broken piece of thrombus (thromboembolism)
Asymptomatic 62yom with a bp of 190/110…name conditions
hypertension
How do we treat hypovolemic shock in pediatrics?
Up to 3 20mL/kg boluses to maintain BP…after each bolus, reassess
How to beta blockers work?
they decrease the activity of the heart by blocking the actions of hormones like adrenaline
decreased HR and BP
-olol drugs
Beck’s Triad
hypotension, JVD, muffled heart sounds
Vascular disorder is ____. Signs of it include (6) P’s
acute limb ischemia
Pain
Pallor
Paralysis
Pulselessness
Paresthesia
Poikilothermia (unable to maintain temp)
What is diltiazem used for? What is the dose?
A-fib (RVR). Dose is 0.25mg/kg max dose of 20mg
What chemical does the body produce to slow things down in the parasympathetic NS
Acetylcholine
Rheumatic fever usually effects the _______. This can cause _____, ____, and damage to the heart itself.
mitral valve, stenosis, regurgitation
Sinus Brady with 1 PVC
What class intervention is Dopamine and Epinephrine Infusions
Class IIb
Atrial Fibrillation (controlled) with 2 unifocal PVC’s
For Brady what is the quick treatment atde
All
Trained
Dogs
Eat
Atropine
TCP
Dopamine
Epinephrine
The sympathetic NS is mediated where?
by nerves in the thoracic/lumbar
A-Fib
f waves, irregular R-R
350-600 bpm Atrial rate
multiple sources trying to fire in the atrium other than SA Node
lots of squiggles
What is nitroglycerin used for? What is the dose?
Chest pain/Angina. Dose is 0.4mg up to 3 times.
What is adenosine used for? What is the dose?
SVT. Dose is 6mg then 12mg Rapid IV
Aortic aneurysm
- dilation or out-pouching of vessel
- at risk for rupture or dissection
- can be treated surgically or conservatively
Parasympathetic Stimulation causes
Decreased:
Slows DOWN HR
AV conduction
Decreased Irritability
only affects the atria
What are classic and atypical signs of M.I.
classic - crushing CP radiates to L shoulder or jaw (can be both shoulders)
Atypical - nausea, epigastric pain, dizziness (women)
Define Dilated cardiomyopathy, what will the ECG look like
- where the chambers are enlarged
- systolic dysfunction
- CHF-like symptoms
- S3 and S4 sounds
- decreased EF
- causes include ETOH, ischemia, HTN, infections
ECG not normal, LVH, LBBB, and axis deviation
When a patient is presenting with acute CHF, they will benefit from what?
nitro and CPAP
Define Stroke Volume
amount of blood pumped in a single contraction
What do you do for a pt with PVCs and ankle sprain?
treat pt not monitor, we don’t do anything for PVCs
medications to treat sickle cell disease
Oxybryta, L-glutamine, TCAs
Dose for epi
cardiac arrest: 1mg IVP every 4 min
anaphylaxis: 0.5mg IM
Shock: 1mg epi in 100mL bag of LR, first drip 1mL/min w/ 60 drop set, titrate up
V-Tach
wide, bizarre QRS
How does atropine work?
- blocks the effects of acetylcholine at the neuromuscular junction
“by blocking acetylcholine the heart speeds up”
Accelerated Junctional
inverted P wave
rate 61-100
Afterload is
resistance that the heart pumps against
Where are the 4 areas you listen to heart sounds
APTM
Aortic valve - right sternal border 2nd ics
Pulmonary valve - 2 ics, left sternal border
Tricuspid valve - (L) 4th ics
Mitral valve - (L) 5th ics
Ejection Fraction is the ______ of blood pumped in _____. The average is _____-______. Below ____ is heart failure.
percentage, one beat
55-70%
40%
What are the 3 Inherent rates of the conduction system
SA Node 60-100 bpm
AV Junction 40-60 bpm
Ventricles 20-40 bpm
Atherosclerosis
narrowing of vessels due to fatty particle deposits
- decreased blood flow
- fatty deposits become “atheroma” and gradually calcifies and becomes plaque
- is a type of arteriosclerosis
Which side is the aortic valve on?
Left side
When do we give adenosine?
SVT
How does fentanyl work?
binds to opioid receptors producing analgesia, euphoria, respiratory depression and sedation…50-100% more potent than morphine
What is another term for hypoperfusion?
Shock
How does diltiazem work?
calcium channel blocker, decreases conduction and ventricular rate
Which system is Fight or Flight and Rest and Digest?
FF - Sympathetic NS
RD - Parasympathetic NS
What is Fibrinolytics
meds that break up blood clots
TPA (used when no cath lab typically)
What does the parts of conduction does the Parasympathetic influence
Only the atria
(i.e., the SA node, the intraatrial, and internodal pathways, and the AV junction)
Hemophilic patients are at most risk of ____.
internal bleeding…mostly in joints, knees, ankles, and elbows
can have spontaneous brain bleeds
What is the dose of adenosine?
6mg, 12mg, 12mg
MUST be rapid WITH A FLUSH
22yo with a hx of IV drug abuse presents with fever and a new 2/6 systolic ejection murmur
acute endocarditis
What 2 valves are open during the diastolic phase?
Mitral valve and Tricuspid valve
Is truncus arteriosus a cyanotic or acyanotic heart defect?
cyanotic
What is the main heart artery that FEEDS the body
Aorta
Dopamine…how does it work?
depends on dose
1-2mcg/kg/min -> dilates renal, mesenteric, coronary and intracerebral vasculature
2-10mcg/kg/min -> stimulates Beta 1 receptors and increases inotropic, chronotropic, dromotropic properties. Increases automaticity
10-20mcg/kg/min -> stimulates alpha 1 receptors. Increases in vasoconstriction. Increases in SVR and a rise in BP
What are interventions to SLOW the heart
Synchronized Cardioversion
Defib
Adenosine
Diltiazem
Beta-Blockers (lol)
Lidocaine
Mag Sulfate
Dose for calcium chloride
0.5-1g SLOW over 10 min
The parasympathetic NS is mediated where?
Vagus nerve (CN X) cholinergic ns
The heart is under control of what system?
the autonomic nervous system
Alpha 1 adrenergic receptors are found mainly in ____ and to a lesser degree, the ____. They cause _____.
the blood vessels, lungs, vasoconstriction
What is an unstable hypertension
hypotension
hyper
180/120
hypo
90/60
When do we use morphine?
moderate to severe pain
pulmonary edema
CHF
What are the great vessels?
Aorta
Inferior Vena Cava
Superior Vena Cava
How do you treat PEA
CPR - compressions
IV/IO access
1mg Epinephrine (0.1mg/mL) IVP every 3/5 mins
ETT and Capno
Is patent ductus arteriosus a cyanotic or acyanotic heart defect?
acyanotic
Dose for sodium bicarbonate
full arrest: 1mEq/kg, repeat 0.5mEq/kg every 10 min
Hyperkalemia: 50mEq SLOW over 5 min, THEN 100mEq into 1000mL LR bag to run 30-60 min
a patient with “tearing” sensation in his lower back. He presents cool, clammy, pain in his back and flank.
Possible ruptured aortic aneurysm
Is pulmonary valve atresia a cyanotic or acyanotic heart defect?
cyanotic
What do you do for a 3rd degree heart block?
supportive care, pacing if unstable
Define
Excitability
Automaticity
Contractility
Extensibility
Conductivity
Excite = response to electric
Contractility = squeeze
Auto = create impulse
extense = stretch,expand
conduct = pass electric
What are the names and locations of the semilunar valves of the heart?
The semilunar valves are the pulmonary (or pulmonic) valve and the aortic valve. The pulmonic valve sits between the right ventricle and the pulmonary artery. The aortic valve sits between the left ventricle and the aorta.
Dose for nitro
chest pain 0.4mg SL (max 1.2mg)
CHF: 0.4mg ever 3-5 min (ma 1.2mg)
High dose: 0.4mg, then 0.8mg
Myocardium
Thick middle layer, contains structures enabling the heart to contract
Sinus Brady with a wide QRS
what is the drug dose of cardizem
when do you give
.35mg/kg IV
tachy
What is atropine used for? What is the dose?
Bradycardia. Dose is 0.4mg/kg
Alpha 2 adrenergic receptors are found in the ____ and _____. They inhibit the release of _____ and _____.
brain, periphery, norepinephrine, acetylcholine
Is atrioventricular septal defect a cyanotic or acyanotic heart defect?
acyanotic
How does adenosine work?
it slows/prevents conduction through the AV node
How do potassium channel blockers work?
block the potassium channel in the CNS and prolongs action potential
if the channels are blocked, the cells can’t repolarize and will NOT transmit another action potential
i.e. amiodarone
According to the CDC, name a medication that is used to treat sickle cell disease.
L-glutamine
What are the 2 shockable rhythms to DEFRIBRILLATE
V- Fib (squiggly worms)
Pulseless V-Tach (no pulse) (tombstones)
Tricuspid valve disorders are caused by _____, _____, and _____.
cardiomyopathy, heart failure, pulmonary HTN
Primary antiplatelet agent is
aspirin 324mg or 325mg
When do we use sodium bicarbonate?
acidosis,
hyperkalemia,
sodium channel blocker toxicity (TCA and phenobarbital)
how does magnesium sulfate work?
CNS depressant, decreases acetylcholine release, slows rate of SA nodal conduction, encourages NA/K movement
A-fib with 2 unifocal PVCs
how much time is between the two heavy lines on a graph
0.20 seconds
When do we use amiodarone?
vfib and vtach
What is morphine/fentanyl used for? What is the dose?
Pain Management. Dose is 1mcg/kg
Stimulation of the Beta receptors (sympathetic) will do what to the heart
Speeds up the
Chronotropic
Inotropic
Dromotropic
What does peripheral circulation do?
Transports oxygenated blood from the heart to the tissues and deoxygenated blood back to the heart
What is the dose for Dopamine
What is the dose for Epinephrine
Dopamine
5-20mcg/kg/min
Epinephrine
2-10mcg/min
Dopamine can be added to Epi or used alone
What is Systole
Ventricular Contraction
SVT (no P waves seen)
When do we use nitro?
pts with chest pain and CHR to reduce preload
What is the hr of brady
less than 50 (for treatment)
What class of drug is Albuterol
Beta 2 adrenergic agonist
SVT with a wide QRS
Define Hypertrophic cardiomyopathy, what will the ECG look like?
thickened myocardial wall
thickened left ventricular wall, diastolic dysfunction, risk of sudden death in young athletes
ECG signs: LVH
What type of angina is at rest that lasts longer than 20 minutes and new onset.
Unstable angina
Define cardiac output
amount of blood pumped each min
Second Degree Type II
What are the 4 ANTI DYSRHYTHMIA drug classes and 1 example for each
class I - na (sodium) channel - lidocaine
class II beta blockers - metoprolol (LOL)
class III - amiodarone
class IV - calcium ch blockers - diltiazem
When do we use calcium chloride?
hypocalcemia, hyperkalemia, calcium channel blocker toxicity, hypotension secondary to Cardizem and to help with “the bad shit from mag sulfate admin”
Define Ejection fraction
percentage of blood leaving the heart each contraction 60-65%
cardiogenic shock
- severely impaired heart muscle function, decreasing cardiac output and resulting in inadequate tissue perfusion
- most commonly caused by LVF from AMI, but can be caused by several issues like tamponade, trauma, etc
Possible signs: Chest pain, change in color, respiratory distress…
Amiodarone dose for peds (with a pulse)
5mg/kg over 20 min (mixed into 100mL)
When should you avoid Atropine
When there is a high degree block
(2nd type II, 3rd Degree)
go right to pacing
Post arrest should ETT when
EARLY PLACEMENT
Sinus with Atrial Pacing
Which nervous system slows the heart
Which nervous system speeds the heart up
Slows DOWN the heart - Parasympathetic
Speeds - Sympathetic
I have NO discernible P waves or QRS waves and look erratic. Cardiac output plummeted when I switched to this rhythm.
V-Fib
What is diastole?
Relaxation of the heart
Is Tetralogy of Fallot a cyanotic or acyanotic heart defect?
cyanotic
Stroke volume is the amount of ______ pumped out of the ____. Average stroke volume is _____.
blood, heart
average is between 60-100mL (avg 70mL)
-
Ventricular Tachycardia
100-250 bpm
wide tall bizarre QRS
What can you give a TACHY patient if you have IV access and the rhythm is regular and narrow
you may give
Adenosine (class I)
6mg, 12mg
Atropine indications
bradycardia, organophosphate poisoning
Mechanically whats happening
P wave
QRS
Twave
P Wave - Atrial contraction
QRS Ventricular Contraction
T Wave Ventricular relaxation
how many different clotting factors are there?
12
What are the 2 layers of the pericardium?
Visceral (epicardium)- inner most layer
Parietal- fibrous outer layer
prolonged QT intervals (LQTS) what can it cause, and what causes it
can cause fainting and seizures
- increase in risk of sudden death
-certain medications can cause LQTS
QTc (corrected QT time) Men > 0.42 s
women > 0.44 seconds
*** greater than 0.5 seconds can be fatal
Steps for Sync Cardio Vert
For unstable Tachy
- Press Sync
- Marker over every R wave
- Settings
A-fib: 120-200J -> 200J -> 300 -> 360J
A-flutter: 100J -> 200J -> 300J -> 360J
SVT w/narrow QRS: 100J -> 200J -> 300J -> 360J
V-tach: 100J -> 200J -> 300J -> 360J
What bad side effect can amiodarone have?
lengthening the QT interval
How do sodium channel blockers work?
stops sodium from coming through cell membranes
blocks the rate AND amplitude of the initial depolarization, reduces cellular excitability and reduces speed of conduction.