10 - Infectious Disease (Exam 2) Flashcards

1
Q

How do innate and acquired immunity differ?

A

Innate immunity is not specific and does not remember

Acquired immunity shows a high degree of specificity and remembers past infections

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2
Q

What are 5 sources of infectious disease?

A
  1. Endogenous microorganisms
  2. Exogenous microorganisms
  3. Nosocomial infections
  4. Community infections
  5. Fomite transmission
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3
Q

How do endogenous and exogenous microorganisms differ?

A

Endogenous is a person’s own microflora

Exogenous are derived from outside the body

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4
Q

How do nosocomial and community infections differ?

A

Nosocomial infections are contracted at a health care center

Community are contracted anywhere outside of health care facilities

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5
Q

What is fomite transmission and what is an example?

A

Physical object that serves to transmit infection

Example: sharing needles

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6
Q

What are 4 examples of portals of entry?

A
  1. Direct contact
  2. Penetration wounds
  3. Ingestion
  4. Inhalation
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7
Q

What are types of penetration wounds?

A
  1. Incision
  2. Abrasion/laceration/avulsion
  3. Puncture
  4. Burns
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8
Q

How does an incision differ from an abrasion/laceration/avulsion?

A

An incision is made by a sharp object with little damage to surrounding tissue
The others are associated with more trauma and therefore more necrosis

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9
Q

Which burns are least severe? Most severe?

A

First degree are least severe (sunburn)

Third degree are most severe

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10
Q

What is the most common portal of entry?

A

Inhalation

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11
Q

What is the typical sequence that infectious disease follows (5 steps)?

A
  1. Incubation period
  2. Prodromal period
  3. Acute period
  4. Convalescent period
  5. Resolution period
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12
Q

What is included in the incubation period?

A

The time from contact to onset of symptoms

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13
Q

What is included in the prodromal period?

A

Initial appearance of symptoms

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14
Q

What is included in the acute period?

A

Host feels the maximum impact of the infectious disease

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15
Q

Which period has the most intense inflammatory and immune response?

A

Acute period

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16
Q

What is associated with the convalescent period?

A

Containment of the pathogen and its effects

17
Q

What occurs in the resolution period?

A

Total elimination of the pathogen

OR beginning of chronic period without elimination

18
Q

What is inferred by the word “subclinical”?

A

Pathogen is present, but symptoms are not

Like COVID

19
Q

What is a fulminating infection?

A

Where each stage has rapid/intense course

Often lethal

20
Q

What is an insidious infection?

A

Similar to subclinical, but symptoms eventually arise in the acute phase

21
Q

What is a chronic infection?

A

An infection that lasts for an extended amount of time without a convalescent period

22
Q

What are categories of infectious agents?

A
  1. Prions
  2. Viruses
  3. Bacteria
  4. Fungi
  5. Protozoa
  6. Helminths
  7. Ectoparasites
23
Q

What is a large difference between prions and viruses?

A

Prions lack nucleic acid

24
Q

What are viruses?

A

Obligate intracellular pathogens with a nucleic acid core and a protein coat (capsid)

25
Q

What are bacterial cell walls composed of?

A

Peptidoglycan

26
Q

How do fungi grow?

A

Hyphae or budding

27
Q

Where can fungal infections occur?

A

Usually occur external/superficial

28
Q

When are systemic fungal infections usually seen?

A

Immunocompromised patients

29
Q

What are protozoa?

A

Motile, single celled eukaryotes

30
Q

What are helminths?

A

Parasitic worms with complex life cycles

Often involve intermediate hosts

31
Q

What are ectoparasites?

A

Chewing and sucking individuals such as fleas, ticks, lice, and mites