1. Renal Embryo

Question 1

3 kidney systems formed embryoligically?
function of each?

Answer 1

pronephrons - rudimentary

mesonephrons - short function in early fetal period

matanephrons - permananet kidney

Question 2

wt gives rise to excretory units of the kidney?

wt gives rise to the collecting system?

Answer 2

metanephric mesoderm

ureteric buds

Question 3

wt causes supernumerary renal arteris?

complication?

Answer 3

failure of inferior renal vessel degenerration

hydronephrosis

Question 4

pts with a horseshoe kidney have a higher likelyhood of developing what?

Answer 4

wilms tumor

Question 5

what happens in a multicystic dysplastic kidney?

result?

Answer 5

uretic bud fails to induce differentiation of metanephric system

kidney does not function bc its replaced by cysts

Question 6

inheritance patter of polycystic kidney disease seen in children?
where do cysts form?
appearance of kidney?

Answer 6

AR
CD
large kidney

Question 7

inheritance patter of polycystic kidney disease seen in adults?
where do cysts form?
appearance of kidney

Answer 7

AD

all segments of nephron

Question 8

wt causes kidney to ascend?

Answer 8

rapid growth of caudal embryo

Question 9

wt causes renal agenisis?
syndrome?
S/S?

Answer 9

uretic bud fails to form

potter syndrome –> anuria, oligohydramnios, pulmonary hypoplasia

Question 10

mutation causing Wilm’s tumor?

Answer 10

WT1 on 11p13

Question 11

cause of bifid ureter?

Answer 11

early division of metanephric blastema

Question 12

most common site of kidney obstruction?

Answer 12

ureteropelvic junction

Question 13

when does urine production in a fetus begin?

Answer 13

10 weeks when glomerular capillaries start to form

Question 14

hw do kidneys appear at birth?

Answer 14

lobulated

Question 15

most common cause of a mass in a newborn?

Answer 15

multicystic dysplastic kidney

Question 16

fetus presents wiht abnormal facies, cleft lip and low set ears,
likely cause?

Answer 16

renal agenesis causing potter syndrome

Question 17

wt is seenin WAGR syndrome?

Answer 17

Wilms tumor
aniridia
Genitourinary anomalies
Retardation

Question 18

wt is seen in Denys-Drash syndrome

Answer 18

Renal failure
pseudohermaphridism
Wilms tumor