07.1 Tuberculosis

Question 1

What is a primary complex and what can occur afterwards?

Answer 1

Alveolar macrophage with TB inside.

Can form a granuloma or suppress the mycobacterium growth via cytokine release.

Question 2

What kind of granuloma is present with TB?

Answer 2

Liquifactive

Question 3

What is it called when TB spreads to other parts of the body?

Answer 3

Miliary TB.

Question 4

What kind of giant cell has TB in it?

Answer 4

Langhans giant cell

Question 5

What are post primary symptoms of TB?

Answer 5

Cough
Weight loss
Fever at night

Question 6

What is the antibiotic treatment for TB and how long does each antibiotic need to be taken for?

Answer 6

Rifampicin - 6 months
Isoniazid - 6 months
Pyrazinamide - 2 months
Ethambutol - 2 months

Question 7

What common side effect can rifampicin, isoniazid and pryazinamide cause?

Answer 7

Hepatitis

Question 8

Which TB drug can cause orange secretions from the body?

Answer 8

Rifampicin

Question 9

What are so many drugs used to treat TB?

Answer 9

To prevent multi drug resistant strains forming

Question 10

Who is at high risk for developing TB?

Answer 10

HIV
Silicosis
Malnutrition
Overcrowding
IV drug abuse
COPD
Asian
Diabetes
Corticosteroids

Question 11

How is TB spread?

Answer 11

Aerosol route