05 - Cardiovascular system: introduction Flashcards

1
Q

List some of the key functions of the cardiovascular system…

A
  • Provides controlled and continuous flow of blood
  • Transport (hormones, nutrients, metabolic products)
  • Homeostasis (heat distribution, pH, osmolarity)
  • Immune defence
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2
Q

The CVS is organised as two circulations in series, served by…

A

Two pumps in series

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3
Q

Unidirectional flow through the CVS is ensured by the presence of…

A

Valves

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4
Q

Name the four valves of the heart…

A

Antrioventricular valves

  • Tricuspid (R)
  • Biscuspid or Mitral (L)

Semilunar valves

  • Pulmonary (R)
  • Aortic (L)
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5
Q

Define: Stroke volume (SV)

A

The volume of blood pumped by one ventricle (which is roughly 75ml at rest, on average)

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6
Q

Define: Cardiac Output (CO)

A

CO = Heart rate x SV

CO at rest is, on average, 5L/min.

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7
Q

Define: Venous Return (VR)

A

The amount of blood returning to the heart, which under steady state conditions is equal to the cardiac output (CO))

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8
Q

The vascular system is comprised of 4 types of vessel…

A
  1. Arteries
  2. Arteriolar
  3. Capillaries
  4. Veins
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9
Q

Arterial walls are:

A) Elastic
B) Thin
C) Have valves
D) All of the above

A

A) Elastic

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10
Q

Arterioles have lots of smooth muscle. They are high resistance vessel which control…

A

Blood flow to tissues

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11
Q

Capillaries are thin walled vessels adapted for…

A

Exchange

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12
Q

Veins are…

A) High pressure vessels with valves
B) Low pressure vessels with valves
C) High pressure vessels without valves
D) Low pressure vessels without valves

A

B) Low pressure vessels with valves

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13
Q

The greatest pressure drop in the cardiovascular system occurs as blood moves through the…

A

Arterioles

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14
Q

Pressure in the large arteries is ( constant / pulsatile )…

A

Pulsatile

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15
Q

Blood flow in vessels is proportional to…

A

Pressure gradient

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16
Q

Flow is determined by ( relative / absolute ) pressures…

A

Relative pressures

It is the difference in pressure (pressure gradient) between areas of the CVS that affects flow.

17
Q

Blood flow is proportional to the reciprocal (“one over”) of…

A

Resistance

18
Q

Darcy’s Law (flow)

A

Flow (Q) = P gradient / Resistance

19
Q

Which three factors determine resistance?

A
  • Vessel length
  • Vessel radius
  • Blood viscosity
20
Q

Flow to capillary beds is regulated locally by (2)…

A
  1. Smooth muscle in the arterioles

2. Precapillary sphincters

21
Q

Blood velocity =

A

Blood velocity = flow / X-SA

Where X-SA = pi * radius^2

22
Q

Velocity of blood is lowest in capillaries, despite their narrow diameter, because…

A

Total cross sectional area (X-SA) is the highest