03-02- pleuradogscats

Question 1

1. In what species is chylothorax most often diagnosed?
2. What is the cytologic appearance of this disease?
3. possible causes?

Answer 1

1. cats
2. cytology = many small lymphocytes in pinkish white effusion
3. idiopathic

feline cardiomyopathy and right-sided heart failure

obstruction of thoracic duct - prevent release of lymph into the vena cava

Question 2

(2. How can feline infectious peritonitis affect the lung and pleura? What is the cytologic appearance of this disease?)
1. How can feline infectious peritonitis affect the lung and pleura?

Answer 2

• FIP can cause pleuritis; yellow/tan pyogranulomatous foci on pleura
  - Cytologic Appearance: Neutrophils, macrophages and lymphocytes

Question 3

(3. What is the most primary neoplasm arising from parietal or visceral pleura?)
1. what is it?

Answer 3

1. mesothelioma

Question 4

1. A young cat has a head tilt, nasal discharge and a pedunculated mass protruding from the Eustachian tube observed on oral exam. What is your diagnosis and what is the prognosis?

Answer 4

• Nasopharyngeal polyps, normally fine but if severe can remove with surgery

Question 5

2. 1. What agents are associated with feline infectious respiratory disease complex?
3. What is the route of transmission?
4. Which agent is most often associated with lingual and oral ulcers?
5. Which agent is most often associated with conjunctivitis as the primary clinical sign?
6. Which agent can be transmitted between dogs and cats?

Answer 5

1. Feline-herpesvirus 1

feline calcivirus

bordetella bronchiseptica

clamydophilia felis (to a lesser extent)

2. shed in oculonasal secretions and oral secretions

direct contact most common

3. calcivirus
4. chlamydophilia felis
5. bordetella bronchiseptica

Question 6

(Cytologic evaluation of bronchiolar lavage fluid collected from a dog reveals a significant population of eosinophils. What general disease processes should you consider - Neoplasia? Hypersensitivity? Pyothorax? Parasitism?Bronchopneumonia? Pulmonary mineralization?)

Answer 6

hypersensitivity, parasitism

Question 7

(4. What are the gross lesions and histopathologic or cytologic findings of cryptococcosis in cats and blastomycosis in dogs? How is the infection contracted?)

(these are for dog)

1. What are the gross lesions and histopathologic or cytologic findings?
2. How is the infection contracted?

Answer 7

1. gross: numerous, miliary (small) white to grey nodules scattered throughout lung accompanied by intrathoracic lymphadenopathy
   histopathology: MULTIFOCAL GRANULOMATOUS PNEMOUNIA - granulomas contain broad-budding yeasts
2. Mycelia in environment release spores that are inhaled and trapped in terminal airways

Question 8

(4. What are the gross lesions and histopathologic or cytologic findings of cryptococcosis in cats and blastomycosis in dogs? How is the infection contracted?)

(these are for cat)

1. What are the gross lesions and histopathologic or cytologic findings?
2. How is the infection contracted?

Answer 8

-Cryptococcis in cats: Nasal ulceration and drainage, resp. tract disease, sub-q nodules, lymphadenopathy, uveitis, CNS disease, granulomatous pneumonia, lung signs are rare;

Yeast- like organism w/ thick polysaccharide capsule; Contracted from environmental spores

Question 9

5. Describe the pathogenesis stages of canine distemper virus infection in dogs? What influences the outcome of the infection?

Answer 9

• Morbilivirus, aerosolized and inhaled, replicate in respiratory epithelium and macrophages →day 2 move to thymus, spleen, bone marrow, retropharyngeal lymph nodes → day3-4 multiplies in lymphoid system, intestinal lamina propria, hepatic Kupffer cells → day 7 mononuclear cells in blood, viremia → day 10 (if immune system not good) widespread invation of all epithelial tissues, lung, CNS

• Adequate host immunity (good antibody response) —> Inapparent illness
  - Influences the outcome: Immune status, age, virulence of strain