02a: Heart Development Flashcards
Primordial heart cells originate in (X), migrate through (Y) between (ectoderm/mesoderm/endoderm) layers.
X = epiderm Y = primitive streak
Between endoderm and ectoderm layers
Primordial heart cells migrate (rostrally/caudally) and eventually position themselves (rostral/caudal) to (X) in which post-gastrulation layer?
Rostrally;
rostral to
X = oropharyngeal membrane
In splanchnic (lateral) mesoderm
Primary heart field will form:
- Atria
- LV
- Part of RV
Secondary heart field will form:
- Part of RV
2. Outflow tracks (conus cordis, truncus arteriosus)
Fusion of (X) tubes to form heart tube occurs after (Y) event.
X = endocardial Y = lateral body folding
Heart tube has inner (X) and outer (Y) layer.
X = endothelial lining Y = myocardial
Cardiac jelly found between which layers in heart tube?
Endothelial (inner) and myocardial (outer)
(X) forms the epicardium of the heart.
X = mesothelium and underlying CT
Any organ suspended in intraembryonic cavity will be lined by:
Mesothelium
Head folding translocates developing endocardial tubes from (X) to (Y).
X = region cranial to neural plate Y = thoracic region
Epicardium, aka (X), is responsible for forming (Y).
X = serous pericardium Y = coronary arteries
Primordial heart tube receives venous drainage at (caudal/cranial) pole and pumps blood out at (caudal/cranial) pole.
Caudal; cranial
Primordial heart tube is attached to (X) side of pericardial cavity by (Y).
X = dorsal Y = dorsal mesocardium
Fate of dorsal mesocardium.
Central portion breaks down and gives rise to transverse pericardial cavity
Cranial end of primary heart tube is attached to (X). Caudal end is attached to (Y).
X = pharyngeal arches Y = septum transversum
As heart tube continues to elongate, it forms (X) number of dilations. List them, from caudal to cranial.
X = 5
- Sinus venosus
- Primitive atrium
- Primitive ventricle
- Bulbus cordis
- Truncus arteriosus
Primitive atrium will eventually contribute to:
- All LA
2. Trabeculated part of RA
Primitive ventricle will eventually contribute to:
Trabeculated part of LV
Primitive proximal bulbus cordis will eventually contribute to:
Trabeculated part of RV
Primitive distal bulbus cords, aka (X), will eventually contribute to:
X = conus cordis
Smooth parts of RV and LV
Primitive truncus arteriosus will eventually contribute to:
Proximal ascending aorta and pulmonary trunk
T/F: Heart tube is asymmetrical throughout development.
False - bilaterally symmetrical in early development