027 Adrenal Pathophysiology Flashcards

1
Q

What is ketaconazole?

A

Blocks cortisol synthesis

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2
Q

What is mitotane

A

Blocks cortisol synthesis

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3
Q

What is metyrapone

A

Blocks cortisol metabolism

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4
Q

What is mifepristone

A

Blocks the actions of cortisol

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5
Q

What is cabergoline?

A

Normalize cortisol levels by managing tumor output

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6
Q

What is a complication of ketaconazole

A

Addisons disease

Liver toxicity

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7
Q

What is a complication of mitotane?

A

Addisons disease

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8
Q

What is a complication of metyrapone

A

DHEA side effects

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9
Q

How do you treat Conn’s syndrome?

A

Spironolactone

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10
Q

What is Nelson’s synrome?

A

Bilateral adrenolectomy causing excessive increase in ACTH production and darkening of the skin.

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