027 Adrenal Pathophysiology Flashcards
1
Q
What is ketaconazole?
A
Blocks cortisol synthesis
2
Q
What is mitotane
A
Blocks cortisol synthesis
3
Q
What is metyrapone
A
Blocks cortisol metabolism
4
Q
What is mifepristone
A
Blocks the actions of cortisol
5
Q
What is cabergoline?
A
Normalize cortisol levels by managing tumor output
6
Q
What is a complication of ketaconazole
A
Addisons disease
Liver toxicity
7
Q
What is a complication of mitotane?
A
Addisons disease
8
Q
What is a complication of metyrapone
A
DHEA side effects
9
Q
How do you treat Conn’s syndrome?
A
Spironolactone
10
Q
What is Nelson’s synrome?
A
Bilateral adrenolectomy causing excessive increase in ACTH production and darkening of the skin.