๐‘ฎ๐‘ฐ ๐‘ฏ๐’‚๐’†๐’Ž๐’๐’“๐’“๐’‰๐’‚๐’ˆ๐’† Flashcards

1
Q

What defines acute GI bleeding?

A

Bleeding less than 3 days duration with hemodynamic instability requiring blood transfusion

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2
Q

What is the difference between overt and occult GI bleeding?

A

Overt bleeding is visible (melena/bright red blood) while occult is only detected by lab tests

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3
Q

What percentage of GI bleeds are from upper sources?

A

75% of GI bleeds originate from upper sources

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4
Q

Which gender has a higher prevalence of upper GI bleeding?

A

More common in men (2:1 ratio)

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5
Q

What are three main types of ulcers causing upper GI bleeding?

A

Peptic ulcer duodenal ulcer and gastric ulcer

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6
Q

What is Mallory-Weiss tear?

A

A superficial longitudinal mucosal tear of the upper esophagus

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7
Q

What causes variceal bleeds in liver cirrhosis?

A

Portal hypertension leading to porto-systemic anastomosis development

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8
Q

What are the four main vital signs of hemodynamic instability in GI bleeding?

A

Pulse rate
Respiratory rate
Blood pressure
Mental state

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9
Q

What is the first priority in emergency management of GI bleeding?

A

ABC (Airway Breathing Circulation) with focus on C takes priority over finding diagnosis/cause

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10
Q

How is crystalloid fluid therapy given in GI bleeding?

A

3:1 ratio of the blood loss estimated using Ringerโ€™s lactate given over 10-15 minutes

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11
Q

What lab tests should be ordered immediately in GI bleeding?

A

FBC clotting profile blood grouping and crossmatch

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12
Q

What are the three anatomical sites of lower GI bleeding?

A

Colon rectum and anus

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13
Q

What percentage of rectal bleeding cases in patients over 80 is due to colon cancer?

A

10% of cases in patients over 80 years

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14
Q

What is a key physical exam finding in GI bleeding suggesting shock?

A

Skin signs (color warmth moisture) to assess for shock

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15
Q

What social history factors increase risk of GI bleeding?

A

Alcoholism (risk of liver disease/variceal bleeding) and smoking (risk of PUD)

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16
Q

What is melena and what does it suggest?

A

Black tarry stools suggesting upper GI bleed

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17
Q

What color blood suggests rectal/anal source?

A

Bright red blood per rectum suggests rectal or anal source

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18
Q

What medication history is important in GI bleeding?

A

Antiplatelet or anticoagulant use that can exacerbate bleeding

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19
Q

What are the three main inflammatory causes of lower GI bleeding?

A

Colitis
Hemorrhoids
Inflammatory bowel disease

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20
Q

What are the vital signs to monitor during resuscitation?

A

Pulse rate
Blood pressure
Urine output
Level of consciousness
Temperature

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21
Q

When should you secure IV access in GI bleeding?

A

Immediately using 2 large-bore cannula in antecubital fossae

22
Q

What indicates severity in GI bleeding?

A

Duration frequency and volume of bleeding

23
Q

What would you like to ask in past medical history for GI bleeding?

A

โ™ฆ๏ธPrevious GI bleeding

โ™ฆ๏ธHx of ay disease that can cause GI bleeding e.g peptic ulcer disease

โ™ฆ๏ธBleeding disorders

โ™ฆ๏ธDrug hx (anti-coagulants or anti-platelets)

24
Q

How do you assess severity of blood loss clinically?

A

By checking vital signs mental status and skin signs

25
What symptoms suggest upper GI source?
Upper abdominal pain or dyspeptic symptoms
26
What symptoms suggest lower GI source?
Lower abdominal pain, diarrhea or change in bowel habits
27
What is the goal of medical therapy in GI bleeding?
To correct shock and stabilize patient for further evaluation
28
What are the three key findings in abdominal examination for GI bleeding?
โ™ฆ๏ธInspection (spider nevi, abdominal distension) โ™ฆ๏ธPalpation (tenderness) โ™ฆ๏ธPercussion (ascites)
29
What is the timeframe for urgent OGD in upper non-variceal GI bleeding?
Within 24 hours - both diagnostic and therapeutic
30
What are the four endoscopic treatment options for bleeding?
Injection (adrenaline) alcohol thermoregulation and clipping of bands
31
What is the role of proton pump inhibitors in GI bleeding?
PPI infusion stabilizes clot by maintaining pH at > 6
32
What is the role of tranexamic acid in GI bleeding?
Acts as an antifibrinolytic agent to help stabilize clots
33
Why at are the pharmacological management of non-variceal GI bleeding?
โ™ฆ๏ธProton pump Inhibitors (infusion) โ™ฆ๏ธTranexemic acid (anti-fibrinolytic) โ™ฆ๏ธIf H.pylori is positive, Eradication therapy โ™ฆ๏ธStop NSAIDS/Aspirin/Clopidogrel/Warfarin/Steroids if safe to do so
34
What medications should be stopped during acute GI bleeding?
NSAIDs, Aspirin, Clopidogrel and steroids if safe to do so
35
What are the 5 main options for managing variceal bleeds?
โ™ฆ๏ธEndoscopy (within 12 hrs) โ™ฆ๏ธDrugs (Somatostatin, Terlipressin, Propanolol) โ™ฆ๏ธBallon Tamponade (Using Sengstaken-blakemore tube) โ™ฆ๏ธRadiology (TIPSS- Transjugular intrahepatic porto-systemic shunt) โ™ฆ๏ธSurgical ( Surgical porto-systemic shunts, Oesophageal resection, Splenectomy & gastric devascularization, Liver transplantation)
36
What is the TIPSS procedure?
Transjugular intrahepatic porto-systemic shunt - is a radiological procedure that creates a shunt between hepatic and portal vein to reduce portal pressure
37
What are the four main surgical options for variceal bleeding?
โ™ฆ๏ธSurgical porto-systemic shunts โ™ฆ๏ธOesophageal resection โ™ฆ๏ธSplenectomy & gastric devascularization โ™ฆ๏ธLiver transplantation
38
What is the timing for endoscopy in variceal bleeding?
Within 12 hours of presentation
39
What endoscopic procedures are used for lower GI bleeding?
โ™ฆ๏ธOesophago-gastro-duodenoscopy โ™ฆ๏ธColonoscopy โ™ฆ๏ธRadiotherapy: Colon polyps โ™ฆ๏ธProctoscopy and flexible sigmoidoscopy
40
Why is occult blood testing indicated regardless of stool appearance?
To detect hidden bleeding even if stool appears normal
41
What is the role of CT angiogram in GI bleeding?
Diagnostic only - non-invasive method to identify bleeding source
42
What surgical options exist for lower GI bleeding?
Segmental colectomy and subtotal colectomy
43
What physical findings suggest epigastric pain origin?
Tenderness which may indicate peptic ulcer or hepatosplenomegaly
44
How is endoscopic therapy modified if rebleeding occurs?
Repeat urgent OGD (oesophago-gastro-duodenoscopy)
45
What is the main indication for surgery in GI bleeding?
Reserved for patients with failed medical management
46
When should radiotherapy be considered in GI bleeding?
For treating colon polyps when indicated
47
What are the complications of surgery?
โ™ฆ๏ธAnastomosis bleeding โ™ฆ๏ธIntra-abdominal bleeding โ™ฆ๏ธSepsis โ™ฆ๏ธMechanical small bowel obstruction
48
4 Clinical features of Upper GI bleeding
โ™ฆ๏ธHematemesis โ™ฆ๏ธCoffee ground vomit โ™ฆ๏ธMelena (black tarry stools per rectum) โ™ฆ๏ธHematochezia
49
State 5 causes of Upper GI bleeding
โ™ฆ๏ธUlcer: Oesophageal ulcer, Duodenal ulcer, Gastric โ™ฆ๏ธErosion: Oesophageal, Duodenal, Gastric Erosion โ™ฆ๏ธMallory Weiss tear โ™ฆ๏ธ Osophageal varices โ™ฆ๏ธTumour
50
Define Lower Gi bleeding
This refers to bleeding distal to the ligament of treitz
51
What drugs are used in managing variceal bleeding?
โ™ฆ๏ธ Somatostatin โ™ฆ๏ธTerlipressin โ™ฆ๏ธPropanolol