XIII: Breath Control Flashcards
Respiration controlled by the
Central nervous system
What triggers the central nervous system in respiration
O2, CO2 alterations
Increased respiratory rate
Tachypnea
Decreased respiratory rate
Bradypnea
Increased respiratory volume
Hyperventilation
Decreased respiratory volume
Hypoventilation
Respiratory center composed of
Neurons in the pons
And medulla oblontaga in brainstem
3 structures to be distinguished
Dorsal respiratory group
Pneumotaxic center
Ventral respiratory group
Function of the Dorsal respiratory group
Functions in inspiration (pacemaker)
Signals in dorsal respiratory group
They increase progressively due to successive and continuous depolarizations
How does the signal start in the dorsal respiratory group
It starts weak and progresses for 2 seconds
What reaches the dorsal respiratory group
Efferent pathways that synapse at motor neuron of C3-C5 phrenic nerve roots (innervates the diaphragm)
Signal, seconds during inspiration and expiration
Signal increases successively and progressively for 2 seconds (inhalation) and stops for 3 seconds (exhalation)
Location of pneumotaxic center
Pons
Function of pneumotaxic center
Inhibit the dorsal respiratory group
Limits inspiration to INCREASE RESPIRATORY RATE
Why does the pneumotaxic center inhibit the dorsal respiratory group
To allow expiration to begin
Ventral respiratory group function
Send signals to Dorsal Respiratory Group and Pneumotaxic Center for overstimulation TO INCREASE VENTILATION
The apneustic center stimulates
Dorsal respiratory group
Location of dorsal respiratory group
Nucleus of solitary tract that extends through medulla oblongata
Location of pneumotaxic center
At parabrachial nucleus in pons
Strong vs. weak pneumotaxic signal
Strong - 30-40 breaths/min
Weak - 3-5 breaths/min
Location of ventral respiratory group
5mm anterolateral to dorsal respiratory group
Function of ventral respiratory group
Remain inactive during silent breathing
But when respiratory requirements increase, respiratory signals from dorsal respiratory group reach the ventral respiratory group due to OVERSTIMULATION
Ventral respiratory group in charge of expiration signals to abdominal muscles during forced expiration
Breathing control is
Autonomous/involuntary
Autonomous signals via
Ventro-lateral tract
Voluntary respiratory signals via
Cortico-spinal tract
Direct effect on respiratory rate of
CO2 and H+
Indirect effect on respiratory rate of
O2
On what does O2 act on
Chemoreceptors in carotid and aortic bodies
Chemosensitive zone is ONLY stimulated by
H+
Why does not a high [H+] have a strong excitatory effect
Because its the CO2 reacting w/ H2O, producing HCO3- and H+ that has an excitatory effect on the CHEMOSENSITIVE AREA
H+ impact central or peripheral chemoreceptors
Central chemoreceptors
Peripheral chemoreceptors are located where
Outside the CNS
To what are peripheral chemoreceptors sensitive to
O2 changes
Carotid body fibers reach
Dorsal respiratory group at medulla oblongata
Aortic bodies nerve fibers reach
Vagus nerve
Which is most important in producing respiratory changes
CO2