X: Factors limiting transfer of a gas

Question 1

Main factors limiting transfer of a gas

Answer 1

Diffusion and perfusion

Question 2

CO is limited by perfusion/diffusion

Answer 2

Diffusion because it does not dissolve in blood so its only barrier is diffusion

Question 3

Is CO able to produce an increase in blood pressure

Answer 3

No because it cannot dissolve in blood

Question 4

Affinity of hemoglobin to CO

Answer 4

Great affinity

Question 5

NO is limited by diffusion/perfusion

Answer 5

Perfusion because it can be dissolved in blood

Question 6

Does NO cause an increase in pNO in blood?

Answer 6

Yes because it dissolves in blood

Question 7

Why is NO dependent on perfusion

Answer 7

Because it immediatly raises pNO therefore there needs to be new blood flowing through capillary for pressure gradient to restart and NO to cross

Question 8

O2 passage depends on perfusion/diffusion

Answer 8

Both diffusion and perfusion

But more on perfusion

Question 9

Of the 0.75 seconds what is the time line of erythrocyte passing through capillary

Answer 9

First 0.25 seconds, 100% saturation is achieved

Remaining 0.5 seconds erythrocytes pass through capillaries

Question 10

What occurs at higher altitudes

Answer 10

0.25 is the time erythrocytes take to become 100% at SEA LEVEL
But, at higher altitudes it takes longer time for them to become 100% saturated

Question 11

Safety mechanism of erythrocyte saturation

Answer 11

Erythrocytes becoming saturated in 1/3 of a second is a safety mechanism to ensure enough saturation during exercise

Question 12

Time spent in capillaries by erythrocytes during exercise

Answer 12

<0.75 seconds but can reach to 0.25

Question 13

During exercise, O2 conditioned by perfusion or diffusion

Answer 13

Diffusion

Question 14

During normal situations, O2 conditioned by perfusion or diffusion

Answer 14

Perfusion