XI: Gas Transport Flashcards

1
Q

Why does blood reach left atrium at 95mmHg instead of 105mmHg?

A

Because of drainage of bronchial circulation and mixture of blood from different ventilation areas

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2
Q

PCO2 is always 40mmHg except

A

When it leaves the tissues at 45mmHg

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3
Q

Blood reaching the tissues with a PO2 of

A

95mmHg

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4
Q

Why are pressure differences smaller for CO2

A

Due to a greater diffusion capacity

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5
Q

How much oxygen is dissolved in blood

A

3%

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6
Q

How much oxygen bound to Hb

A

97%

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7
Q

In situations of high PO2, O2 binds or dissociates from Hb

A

Binds

In situations of low PO2 is dissociates from Hb

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8
Q

Hb saturation when leaving capillaries, leaving lungs and tissues

A

Capillaries - 100%
Lungs - 98%
Tissues - 75%

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9
Q

How much O2 mL dissolved for every 100mL of blood

A

0.3mL of O2

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10
Q

Venous level saturation during exercise

A

Decreases because we need to get more O2 to tissues

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11
Q

1st step for exchange

A

Partial pressure have to be equalized to 100mmHg

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12
Q

What happens after partial pressures have been equalized,

A

Hb from deoxeginated oxygen binds to O2

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13
Q

Partial pressure equalization in tissues process

A

Partial pressure first equalized, then O2 dissociates and Hb becomes less saturated

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14
Q

PO2 at 100mmHg at

A

100% Hb saturation

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15
Q

PO2 at 95mmHg at

A

98% Hb saturation

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16
Q

PO2 at 40mmHg at

A

75% Hb saturation

17
Q

Relationship of Hb dissociation curve is

A

Sigmoidal

18
Q

At P50

A

50% saturation –> 26/27mmHg

19
Q

At P90

A

90% saturation –> 60mmHg

20
Q

Curve has 2 parts (horizontal and vertical)

A

Horizontal part where changes in pressure do not lead to large changes in saturation
Vertical part where large changes in pressure lead to great changes in saturation

21
Q

Factors impacting O2-Hb dissociation curve

A

Temperature
PCO2
2-3,DPG
pH

22
Q

Factors increasing Hb affinity for O2

A

Decreased temperature
Decreased PCO2
Decreased 2,3-DPG
Increased pH

23
Q

Factors decreasing Hb affinity for O2

A

Increase temperature
Increase PCO2
Increase 2,3-DPG
Decrease in pH