X-linked Diseases Flashcards

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1
Q

X-linked diseases

A

are genetic disorders caused by mutations in genes located on the X chromosome. Females have two X chromosomes, while males have one X and one Y chromosome.

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2
Q

There are two main types of X-linked inheritance:

A

X-linked recessive: -most common type of X-linked inheritance.
-A male only needs one mutated copy of the gene to have the condition, because males only have one X chromosome.
-Females have two X chromosomes, so they need two mutated copies of the gene to have the condition.

X-linked dominant:
-X-linked dominant disorders are less common than X-linked recessive disorders.
-In X-linked dominant disorders, a female only needs one mutated copy of the gene to have the condition. Males with an X-linked dominant disorder will usually have symptoms that are more severe than those of females with the disorder.

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3
Q

Hemophilia

A

a common X-linked recessive disorder that affects blood clotting. Males with hemophilia have a mutated gene on their X chromosome, leading to clotting problems

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