Fish Flashcards

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1
Q

FISH

A

Fluorescence in situ hybridization

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2
Q

What does FISH DO?

A

FISH, which stands for Fluorescence in situ hybridization, is a technique used to examine an organism’s genetics by looking at its chromosomes.

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3
Q

Here’s a rundown of how FISH works:

A

-A segment of DNA, called a probe, is created to match a particular gene or region of interest.

-This probe is tagged with a fluorescent dye.

-The probe is then introduced to the chromosomes which have been placed on a slide.

-If the probe finds its matching sequence on a chromosome, it will bind to it.
A special microscope can then be used to see the glowing spot, revealing the location of the gene or region of interest.

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