X A&P - Chp 13 - The Blood Flashcards
What does blood do?
- Brings nutrients and oxygen to cells
- Carry away waste
Transportation, regulation, protection
What kind of tissue is blood? 2 types of circulating tissue.
- Circulating tissue
- Blood, plasma
Ways blood TRANSPORTS
- GASES, O to lungs and thru body
- NUTRIENTS, water, vits, electrolytes to cells
- WASTE, transports waste to kidney to be removed
- HORMONES, carries hormones to areas of body
Ways blood REGULATES
- pH
- FLUID BALANCE, amount of fluid in tissues
- HEAT, heat generated in muscles to other parts of body
Ways blood PROTECTS
- DISEASE, carries cells and substances to fight infections
- BLOOD LOSS, clotting
pH range of blood
7.35-7.45
Two parts of Blood
- Plasma
- Formed Elements
Blood constituents
- Erythrocytes (RBC)
- Leukocytes (WBC)
- Platelets
Formed elements produced where?
Red Bone Marrow
which cells can potentially develop into any blood cell type
Hematopoietic Stem Cells
blood forming
Mature Erythrocytes
have no nucleus. dissolves to make more room to carry O.
O is bound to what part of RBC?
hemoglobin, protein containing Fe (Iron)
Functions of Hemoglobin
1) carry Oxygen (MAIN FUNCTION)
2) carry H when O given up (role in acid/base balance)
3) carry CO2 from lungs to tissue for disposal
Most numerous Blood Cells
Erythrocytes (RBC)
Red cell production stimulated by what hormone?
EPO, Erythropoietin, released by kidney in response to decreased O.
Constant RBC production requires
1) protein,
2) vit B12, Folic Acid (production of DNA)
3) Iron, Copper (prod of hemoglobin)
4) Vit C (absorbtion of Fe into small intestines)
Hemoglobin is a
protein
Stercobilin
brown fecal pigment that leaves body after Liver and Spleen break down dead RBC .
Leukocytes identified by
size, shape of nucleus, apperance of cytoplasm (granular or agranular)
Granulocytes
- Neutrophils (most) (aka polymorphs)
- Eosinophils
- Basophils
Agranulocytes
- Lymphocytes (second highest to neutrophils)
- Monocytes
Band Cells
young neutrophils before nucleus’ become segmented
incresaed numbers of what Granulocytes indicate infection
Neturophiols
increased numbers of what granulocytes indicate allergic reaction
- Eosinophils
- Basophils
Titers
of antibodies in blood
Titers
of antibodies in blood
Titers
of antibodies in blood
Titers
of antibodies in blood
Blood platelets (thrombocytes
Fig 13.5
What kind of tissue is blood
Liquid connective tissue, 8% of body weight
What kind of tissue is blood
Liquid connective tissue, 8% of body weight
What kind of tissue is blood
Liquid connective tissue, 8% of body weight
What kind of tissue is blood
Liquid connective tissue, 8% of body weight
Normal pH of blood
7.35-7.45
Normal pH of blood
7.35-7.45
Normal pH of blood
7.35-7.45
Normal pH of blood
7.35-7.45
Hematocrit
%of RBCS, formed solids in blood
Hematocrit
%of RBCS, formed solids in blood
Hematocrit
%of RBCS, formed solids in blood
Hematocrit
%of RBCS, formed solids in blood
ESR
Erythrocyte Sedimentation Rate (how quickly it takes RBCs to sink to bottom)
ESR
Erythrocyte Sedimentation Rate (how quickly it takes RBCs to sink to bottom)
ESR
Erythrocyte Sedimentation Rate (how quickly it takes RBCs to sink to bottom)
ESR
Erythrocyte Sedimentation Rate (how quickly it takes RBCs to sink to bottom)
Makeup of PLASMA
- water
- proteins (albumin(highest),clotting factors, antibodies, complement(generic antibody), salts sugars etc)
Makeup of PLASMA
- water
- proteins (albumin(highest),clotting factors, antibodies, complement(generic antibody), salts sugars etc)
Makeup of PLASMA
- water
- proteins (albumin(highest),clotting factors, antibodies, complement(generic antibody), salts sugars etc)
Makeup of PLASMA
- water
- proteins (albumin(highest),clotting factors, antibodies, complement(generic antibody), salts sugars etc)
Platelets
Broken pieces of RBCs
Platelets
Broken pieces of RBCs
Platelets
Broken pieces of RBCs
Platelets
Broken pieces of RBCs
Blood made of
- Erythrocytes
- leukocytes (granulocytes: neutrophils, eosinophils, basophils, lymphocytes, agranulocyte: monocytes)
- platelets (thrombocytes)
Blood made of
- Erythrocytes
- leukocytes (granulocytes: neutrophils, eosinophils, basophils, lymphocytes, agranulocyte: monocytes)
- platelets (thrombocytes)
Blood made of
- Erythrocytes
- leukocytes (granulocytes: neutrophils, eosinophils, basophils, lymphocytes, agranulocyte: monocytes)
- platelets (thrombocytes)
Blood made of
- Erythrocytes
- leukocytes (granulocytes: neutrophils, eosinophils, basophils, lymphocytes, agranulocyte: monocytes)
- platelets (thrombocytes)
Reticulocyte
Baby RBCs w nucleus found in peripheral blood
Thrombocytes fragments released from
Megakaryocytes
Reticulocyte
Baby RBCs w nucleus found in peripheral blood
Reticulocyte
Baby RBCs w nucleus found in peripheral blood
Neutrophils aka
Polymorphs
Clean up crew, lots present means infection, front line die quickly
Granules: lysosomes to digest, peroxide to clean
Neutrophils aka
Polymorphs
Clean up crew, lots present means infection, front line die quickly
Granules: lysosomes to digest, peroxide to clean
Neutrophils aka
Polymorphs
Clean up crew, lots present means infection, front line die quickly
Granules: lysosomes to digest, peroxide to clean
Neutrophils aka
Polymorphs
Clean up crew, lots present means infection, front line die quickly
Granules: lysosomes to digest, peroxide to clean
Granulocytes in WBCs
- Neutrophils
- Eosinophils (fight parasites,worms)
- Basophils (contain histamine, increase w allergy, itching, redness, hives)
Granulocytes in WBCs
- Neutrophils
- Eosinophils (fight parasites,worms)
- Basophils (contain histamine, increase w allergy, itching, redness, hives)
Granulocytes in WBCs
- Neutrophils
- Eosinophils (fight parasites,worms)
- Basophils (contain histamine, increase w allergy, itching, redness, hives)
Granulocytes in WBCs
- Neutrophils
- Eosinophils (fight parasites,worms)
- Basophils (contain histamine, increase w allergy, itching, redness, hives)
Agranulocytes in WBC
- Lymphocytes (T, B cells)
- Monocytes (eaters, phagocytes)
Difference in Neutrophil nucleus’
- Baby - Band Nucleus, Band Cell
- Mature - segmented, various shapes, multiple (poly’s)
3 steps of Hemostasis
1) Vasoconstriction
2) Platelet Aggregation (platelet plug)
3) Clot formation
Thrombocytes fragments released from
Megakaryocytes
Life Span of Platelets
couple of days
Formation of Blood Clot
1) Formation of prothrombinase
2) Conversion of prothrombin into thrombin (via prothrombinase)
3) Conversion of fibrinogen into fibrin (via thrombin)