Wordsology Blood Bank High Yield Notes Flashcards

1
Q

Write down the Weiner genotypes and match them to their corresponding Fisher-Race antigen phenotypes.

A

Weiner: Ro, R1, R2, Rz r, r’, r’’, ry

Fisher Race: Dce, DCe, DcE, DCE dce, dCe, dcE, dCE

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Which two genes (Weiner) are the most common in the population?

A

R1 –> DCe

r –> dce

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What percent of the population is Rh+?

A

85%

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Asian’s are almost always what Rh type?

A

Asians are almost always Rh+ (D+)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What single Rh antigen is the most common in whites?

A

e

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What single Rh antigen is the most common in Africans?

A

e** > c > D

e = 95%,
c = 96%
D = 92%
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What single Rh antigen is the least common in whites?

A

E

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What single Rh antigen is the least common in blacks

A

E (22%)

Followed closely by C (27%)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What two Rh phenotypes are the most commonly seen in whites?

A
  1. R1 = DCe (42%)

2. r = dce (37%)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What two Rh phenotypes are the most commonly seen in Africans/Blacks?

A
  1. Ro = Dce (44%)

2. r = dce (25%)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What two Rh phenotypes are the most commonly seen in Asians?

A
R1 = DCe (70%) 
R2 = DcE (21%)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Which Rh phenotypes are very uncommon?

A

Rz

r’’

ry

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

How is the Lewis system produced?

A

NOT produced by the red cell. They are ADSORBED onto the RBC from the plasma.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

If only the Le gene is inherited and not the secretor gene, what antigen is adsorbed onto the RBCs and what is the phenotype?

A

Le ONLY
NO Secretor gene

Le(a) is adsorbed onto the RBCs!

Le (a+ b-)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

If the Le gene AND secretor gene is inherited, what antigen is adsorbed onto the RBCs and what is the phenotype?

A

Le AND Secretor gene

Le(b) is adsorbed onto the RBCs!

Le (a- b+)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Which antibodies are naturally occurring?

A

ABO, Lewis, P1, MN, Lu(a)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Which antibodies are clinically significant?

A

ABO, Rh, Kell, Duffy, Kidd, SsU

18
Q

Which antibodies are warm antibodies?

A

Rh, Kell, Duffy, Kidd

19
Q

What antibodies are cold antibodies?

A

M, N, P1

20
Q

What antibodies usually only react in AHG (not detected on immediate spin)?

A

Kell, Duffy, Kidd

21
Q

What antibodies can react in any phase of testing?

A

Lewis

22
Q

What antibodies can be ENHANCED by enzyme treatment?

A

Rh, Lewis, Kidd

23
Q

What antibodies CANNOT be detected by enhancement of enzyme treatment?

A

M, N, Duffy

24
Q

What antibodies can be ENHANCED by acidification?

A

M

25
Q

Which antibodies show DOSAGE?

A

Rh (other than D), MNS, Duffy, Kidd

26
Q

Which antibodies bind complement?

A

I, Kidd, Lewis

27
Q

Which antibodies cause IN VITRO hemolysis?

A

ABO, Lewis, Kidd, Vell, and some P1

28
Q

Which antibodies are labile (can change) in vivo and in vitro?

A

Kidd

29
Q

What antibodies are a common cause of anamnestic response (delayed transfusion rxns)

A

Kidd

** Kids are delayed **

30
Q

Which antibodies are associated with paroxysmal cold hemoglobinuria (PCH)?

A

Anti-P

31
Q

What age does a donor have to be to give blood?

A

> or equal to 16

32
Q

What weight does a donor have to be to give blood?

A

at least 110 lbs

33
Q

Donor interval for whole blood?

A

8 weeks

34
Q

Donor blood pressure?

A

less than or equal to 180/100

remember SKY over DIRT; systolic/diastolic

35
Q

What does a blood donor’s pulse have to be for them to give blood?

A

50-100 bpm

36
Q

Donor hemoglobin? (allogenic)

A

> or equal to 12.5

37
Q

Donor hematocrit? (allogenic)

A

> or equal to 38%

Females > or equal to 36%
Males > or equal to 39%

38
Q

Donor temperature?

A

< or equal to 37.5 or 99.5C

39
Q

What is a cause of deferral for autologous donations?

A

Bacteremia

40
Q

Calculation for how much blood can an autologous donor give themselves?

A

(Weight in Kg/50kg) x 450mL