Wold 2 Flashcards
There are 5 basic categories of useable food (energy sources
Carbohydrates Protein Fats Vitamins Minerals
The brush border ectoenzymes are essential for
digestion and absorption of carbohydrates
Complex carbohydrates broken down into
monosaccharides Digestive enzymes (such as amylase) Ectoenzymes (lactase)
Monosaccharides taken up by epithelial cells by
transporters
Monosaccharides passed into blood via
GLUT2
Proteins are broken down into peptides in
2 locations
Stomach
———- is produced in stomach—cleaved to —— which degrades protein
Pepsinogen
pepsin
Small Intestine
Pancrease releases
pro-enzymes into small intestine to digest proteins
Pancreas pro enzymes
Trypsinogen
Cymotrypsinogen
Procarboxypeptidases A and B
Proelastase
Must be converted to active enzymes—initiated by enteropeptidase
Trypsin is an ——- for cleavage of proteins
essential protease
Two Broad Classes of AA Transporters
Na+ Dependent
Na+ Independent
AA Subclasses are specific for
certain types of amino acids
AA Transporters are on
brush border and basolateral membrane
Sources of Lipase
Lingual Lipase
Gastric Lipase
Pancreatic Lipase
But, then how does lipase interact with the fat?
Colipase
How do micelles enhance absorption of fatty acids?
Micelles are in equilibrium with free fatty acids.
Micelles are constantly breaking down and reforming.