Wold 2 Flashcards

1
Q

There are 5 basic categories of useable food (energy sources

A
Carbohydrates
Protein
Fats
Vitamins
Minerals
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2
Q

The brush border ectoenzymes are essential for

A

digestion and absorption of carbohydrates

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3
Q

Complex carbohydrates broken down into

A
monosaccharides
Digestive enzymes (such as amylase)
Ectoenzymes (lactase)
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4
Q

Monosaccharides taken up by epithelial cells by

A

transporters

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5
Q

Monosaccharides passed into blood via

A

GLUT2

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6
Q

Proteins are broken down into peptides in

A

2 locations

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7
Q

Stomach

———- is produced in stomach—cleaved to —— which degrades protein

A

Pepsinogen

pepsin

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8
Q

Small Intestine

Pancrease releases

A

pro-enzymes into small intestine to digest proteins

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9
Q

Pancreas pro enzymes

A

Trypsinogen
Cymotrypsinogen
Procarboxypeptidases A and B
Proelastase

Must be converted to active enzymes—initiated by enteropeptidase

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10
Q

Trypsin is an ——- for cleavage of proteins

A

essential protease

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11
Q

Two Broad Classes of AA Transporters

A

Na+ Dependent

Na+ Independent

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12
Q

AA Subclasses are specific for

A

certain types of amino acids

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13
Q

AA Transporters are on

A

brush border and basolateral membrane

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14
Q

Sources of Lipase

A

Lingual Lipase
Gastric Lipase
Pancreatic Lipase

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15
Q

But, then how does lipase interact with the fat?

A

Colipase

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16
Q

How do micelles enhance absorption of fatty acids?

A

Micelles are in equilibrium with free fatty acids.

Micelles are constantly breaking down and reforming.

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17
Q

Triglycerides are found in

A

systemic circulation, not free fatty acids or monoglycerides.

18
Q

Many vitamins are fat soluble

A

A
D
E
K

19
Q

vitamins

Solubilized in

A

micelles, and passively diffuse through intestinal epithelial cells

20
Q

Vitamins

Released into body with

A

chylomicrons

21
Q

Water soluble vitamins

All are absorbed by

A

facilitated or active transport, except B12

22
Q

All of the proteases are released as

A

proenzymes

23
Q

Luminal peptidases are not

A

sufficient to breakdown protein; brush border enzymes are also needed

24
Q

Peptides and amino acids are

A

transported across epithelial cells by transporters

25
Q

Fatty acid absorption occurs in the

A

small intestine (primarily duodenum), but digestion occurs in stomach and duodenum

26
Q

Fats are not water soluble, but

A

lipases are.

27
Q

Gastric emptying is slowed by

A

fats

28
Q

Fat films are emulsified both

A

Mechanically

Emulsifying agent

29
Q

Most water absorption occurs in the

A

small intestine

30
Q

Much of the concentration gradient of solutes is dependent upon

A

Na+

31
Q

Absorption of Na+

Occurs throughout the

A

entire GI tract

32
Q

Absorption of Na+

Can occur against a

A

small electrochemical gradient

33
Q

Absorption of Na+

Is highest in areas where

A

glucose and galactose or amino acids are being transported

34
Q

Absorption of Na+

Cl-, HCO3, K+ are also absorbed in part due to

A

Na+

35
Q

Absorption of Minerals (Ca++)

Actively absorbed by

A

all segments of the intestine

36
Q

Absorption of Minerals (Ca++)

Salts are soluble at

A

low pH

37
Q

Absorption of Minerals (Ca++)

Strongly enhanced by

A

vitamin D

38
Q

Absorption of Fe++

Very

A

inefficient (< 10% of dietary Fe++ is absorbed)

39
Q

Absorption of Fe++

Stomach ——– absorption

A

enhances

40
Q

Absorption of Fe++

======can not be absorbed

A

Fe+++