wk4 macroanatomy Flashcards
What is the encephalization quotient(EQ)?
EQ =log of species average brain mass divided by
log of species average body mass. Generally, the higher the EQ, the higher the average species intelligence
Describe Deep Brain Stimulation
Somewhat reversible.Invasive. Requires surgery to place electrodes deep in brain. Used therapeutically eg. Parkinsons,OCD,essential tremor.
‘Describe EEG
Recording electrodes placed on scalp. Non invasive.
High level of temporal resolution, but poor spatial.
Describe Magnetic Resonance Imaging (MRI)
Non invasive. High spatial resolution(within 1mm).Can set scanner for white matter or grey matter or cerebrospinal fluid.Pulse measures reactions of hydrogen atoms.
Describe functional MagneticResonance Imaging (fMRI)
Non invasive. Measures neural activity indirectly, by measuring oxygenated blood(=bold contrast). Views tissue differences with respect to time.
Describe Positron Emission Tomography (PET)
Invasive. Radioactive chemicals injected i/v. Select a radiotracer which binds eg to glucose,water,dopamine,GABA etc. See how brain processes over time.Good spatial resolution, poor temporal resolution.
List methods used to understand the relationship between brain and behaviour.
- anecdotes
- lesioning
- brain imaging during behaviours
- brain stimulation to induce a behaviour.
List invasive techniques of brain imaging
- lesioning
- deep brain stimulation
- psychosurgery
- PET (not very ivasive)
list non invasive brain imaging techniques
- rTMS
- MRI
- EEG
When would be appropriate to use EEG
when wish to see very quickly if there is brain activirt and doesn’t matter where precisely.best for assessing medical “brain death”, seizure disorders, sleep disorders and head injury.
define spatial resolution
How precisely one can correlate findings to a precise area
define temporal resolution
How quickly the response follows the stimulus. A measure of how fast the test result is perceived.
Describe TMS and what it is useful for
Transcranial magnetic stimulation..Magnets at scalp induce an electrical impulse within the brain.Used to stimulate specific brain areas. Used esp in depression, to increase activity in regions of suboptimal activity.
Describe the cerebral cortex
The largest part of the forebrain. Composed of sulci and gyri.Fissures are the very deep clefts Composed of the following lobes;
temporal,parietal,occipital,frontal.
list the components of the hindbrain.
pons,medulla oblongata,reticular formation,cerebellum
what part of the brin is responsible for breathing and heart rate?
medulla oblongata
Describe the parts of the brain involved in sleep and their roles
- The reticular formation maintains arousal and consciousness.
- The hypothalamaus. Neurons in the ventrolateral preoptic nucleus (VLPO)within the hypothalamus inhibit the signals from the reticular formation, to promote sleep.
- Pons also plays a part.
Information from your muscles, organs and glands comes through which hindbrain region?
Ascending Pathway-part of the reticular formation, which is deep within the medulla and pons.
describe the cerebellum
Located in hindbrain. Imortant for smoothing out muscle control.
List and describe the parts of the midbrain
- Tectum-superior colliculus(involved in vision and eye movements) and inferior colliculus (involved in hearing)
- cerebral peduncle-nerve fibres connecting cerebrum with cerebellum. Contains tegmentum, crus cerebri, substantia nigra (produces dopamine which is used in muscle control and reward)
describe the role of the thalamus
part of forebrain.Involved in sending infoto cerebral cortex.Involved in spatial awareness. Involved in consciousness, sleep and alertness.
sits in the centre of the brain. has a part in both left and right lobe.Acts as a “relay station”. sends sensory info including taste,touch,vision,hearing to primary cortices for further processing.
describe problems with the thalamus
- in schizophrenia, there appears to be a reduction in the size of the thalamus.Thought this means thalamus sends garbled sensory info, therefore confusing sensory experiences and hallucinations.
- studies in rats learnt a sequence by smells, but when certain parts of the thalamus was damaged, they were impaired in their ability to do this.
- In humans, disruption of anterior thalamic nuclei associated with severe anterograde amnesia.